Discovery and clinical translation of novel glaucoma biomarkers

G Beykin, AM Norcia, VJ Srinivasan, A Dubra… - Progress in Retinal and …, 2021 - Elsevier
Glaucoma and other optic neuropathies are characterized by progressive dysfunction and
loss of retinal ganglion cells and their axons. Given the high prevalence of glaucoma-related …

Macular imaging with optical coherence tomography in glaucoma

V Mohammadzadeh, N Fatehi, A Yarmohammadi… - Survey of …, 2020 - Elsevier
With the advent of spectral-domain optical coherence tomography, imaging of the posterior
segment of the eye can be carried out rapidly at multiple anatomical locations, including the …

[HTML][HTML] Retinal nerve fiber layer features identified by unsupervised machine learning on optical coherence tomography scans predict glaucoma progression

M Christopher, A Belghith, RN Weinreb… - … & visual science, 2018 - tvst.arvojournals.org
Purpose: To apply computational techniques to wide-angle swept-source optical coherence
tomography (SS-OCT) images to identify novel, glaucoma-related structural features and …

Macular imaging by optical coherence tomography in the diagnosis and management of glaucoma

KE Kim, KH Park - British Journal of Ophthalmology, 2018 - bjo.bmj.com
The macular area is important to the detection of glaucomatous retinal ganglion cell (RGC)
damage. Macular thickness complementary to peripapillary retinal nerve fibre layer (RNFL) …

Cardiovascular disease predicts structural and functional progression in early glaucoma

H Marshall, S Mullany, A Qassim, O Siggs, M Hassall… - Ophthalmology, 2021 - Elsevier
Purpose To investigate the association between cardiovascular disease and baseline
structural defects and disease progression in glaucoma. Design Prospective, longitudinal …

Optical coherence tomography and optical coherence tomography angiography: essential tools for detecting glaucoma and disease progression

Y Shiga, T Nishida, JW Jeoung, A Di Polo… - Frontiers in …, 2023 - frontiersin.org
Early diagnosis and detection of disease progression are critical to successful therapeutic
intervention in glaucoma, the leading cause of irreversible blindness worldwide. Optical …

Patterns of progressive ganglion cell–inner plexiform layer thinning in glaucoma detected by OCT

JW Shin, KR Sung, SW Park - Ophthalmology, 2018 - Elsevier
Purpose To investigate the spatial characteristics and patterns of progressive macular
ganglion cell–inner plexiform layer (GCIPL) thinning in glaucomatous eyes assessed by …

The loss of macular ganglion cells begins from the early stages of disease and correlates with brain atrophy in multiple sclerosis patients

AM Pietroboni, L Dell'Arti, M Caprioli… - Multiple Sclerosis …, 2019 - journals.sagepub.com
Background: The importance of neurodegeneration in multiple sclerosis (MS) is increasingly
well recognized. Objectives: To evaluate retinal pathology using optical coherence …

Unmet needs in ophthalmology: a European Vision Institute-consensus roadmap 2019–2025

C Cursiefen, F Cordeiro, J Cunha-Vaz… - Ophthalmic …, 2019 - karger.com
Purpose: To define unmet needs in ophthalmology that can realistically be addressed in the
next 5 years (2019–2025) and describe potential avenues for research to address these …

Topographic correlation between macular superficial microvessel density and ganglion cell-inner plexiform layer thickness in glaucoma-suspect and early normal …

JS Kim, YK Kim, SU Baek, A Ha, YW Kim… - British Journal of …, 2020 - bjo.bmj.com
Background/Aims To investigate the topographic relationship between macular superficial
microvessel density (SMD) and macular ganglion cell-inner plexiform layer (GCIPL) …