[HTML][HTML] Adult hippocampal neurogenesis in aging and Alzheimer's disease

KR Babcock, JS Page, JR Fallon, AE Webb - Stem cell reports, 2021 - cell.com
Cognitive deficits associated with Alzheimer's disease (AD) severely impact daily life for the
millions of affected individuals. Progressive memory impairment in AD patients is associated …

[HTML][HTML] Adult hippocampal neurogenesis in Alzheimer's disease: A roadmap to clinical relevance

E Salta, O Lazarov, CP Fitzsimons, R Tanzi… - Cell Stem Cell, 2023 - cell.com
Adult hippocampal neurogenesis (AHN) drops sharply during early stages of Alzheimer's
disease (AD), via unknown mechanisms, and correlates with cognitive status in AD patients …

Neurogenesis in aging and age-related neurodegenerative diseases

L Culig, X Chu, VA Bohr - Ageing research reviews, 2022 - Elsevier
Adult neurogenesis, the process by which neurons are generated in certain areas of the
adult brain, declines in an age-dependent manner and is one potential target for extending …

[HTML][HTML] Depression and adult neurogenesis: Positive effects of the antidepressant fluoxetine and of physical exercise

L Micheli, M Ceccarelli, G D'Andrea, F Tirone - Brain research bulletin, 2018 - Elsevier
Of wide interest for health is the relation existing between depression, a very common
psychological illness, accompanied by anxiety and reduced ability to concentrate, and adult …

[HTML][HTML] Adult hippocampal neurogenesis and its role in Alzheimer's disease

Y Mu, FH Gage - Molecular neurodegeneration, 2011 - Springer
The hippocampus, a brain area critical for learning and memory, is especially vulnerable to
damage at early stages of Alzheimer's disease (AD). Emerging evidence has indicated that …

[HTML][HTML] Neuroinflammation and neurogenesis in Alzheimer's disease and potential therapeutic approaches

PS Sung, PY Lin, CH Liu, HC Su, KJ Tsai - International journal of …, 2020 - mdpi.com
In adult brain, new neurons are generated throughout adulthood in the subventricular zone
and the dentate gyrus; this process is commonly known as adult neurogenesis. The …

[HTML][HTML] Zika virus infects neural progenitors in the adult mouse brain and alters proliferation

H Li, L Saucedo-Cuevas, JA Regla-Nava, G Chai… - Cell stem cell, 2016 - cell.com
Zika virus (ZIKV)-related neuropathology is an important global health concern. Several
studies have shown that ZIKV can infect neural stem cells in the developing brain, but …

[HTML][HTML] Role of Wnt signaling in adult hippocampal neurogenesis in health and disease

SB Arredondo, D Valenzuela-Bezanilla… - Frontiers in Cell and …, 2020 - frontiersin.org
Neurogenesis persists during adulthood in the dentate gyrus of the hippocampus. Signals
provided by the local hippocampal microenvironment support neural stem cell proliferation …

Hippocampal neurogenesis: learning to remember

O Lazarov, C Hollands - Progress in neurobiology, 2016 - Elsevier
Alzheimer's disease, the most prevalent form of dementia in the elderly, is characterized by
progressive memory loss and cognitive dysfunction. It has become increasingly clear that …

[HTML][HTML] Factors that influence adult neurogenesis as potential therapy

B Shohayeb, M Diab, M Ahmed, DCH Ng - Translational …, 2018 - Springer
Adult neurogenesis involves persistent proliferative neuroprogenitor populations that reside
within distinct regions of the brain. This phenomenon was first described over 50 years ago …