Brown adipose tissue (BAT) displays the unique capacity to generate heat through
uncoupled oxidative phosphorylation that makes it a very attractive therapeutic target for …

Diabetes mellitus (DM) is a chronic metabolic condition characterized by persistent
hyperglycemia due to insufficient insulin levels or insulin resistance. Despite the availability …

The beef quality significantly varies between breeds. Pingliang Red Cattle resembles
Wagyu in fat deposition and flavor. To screen key factors affecting beef quality, we …

Obesity is a chronic metabolic disease caused by a long-term imbalance between energy
intake and expenditure. The discovery of three different shades of adipose tissues has …

The gut barrier–including tight junction proteins (TJPs) and mucus layers, is the first line of
defense against physical, chemical or pathogenic incursions. This barrier is compromised in …

Background No reports exist as to neuroprotective effects associated with topical activation
of transient receptor potential melastatin 8 (TRPM8), a noted cold receptor. In the present …

Obesity is a significant public health problem worldwide that is characterized by abnormal or
excessive fat accumulation. Unfortunately, the application of available weight-loss drugs has …

Cereal bran consumption improves gastrointestinal and metabolic health. Unprocessed
cereal brans have a limited shelf-life and contain anti-nutrient phytochemicals. In the present …

Increasing basal energy expenditure via uncoupling protein 1 (UCP1)-dependent non-
shivering thermogenesis is an attractive therapeutic strategy for treatment of obesity …

Background Bioactive dietary constituents activating Transient receptor potential (TRP)
channels have emerged as promising candidates for the prevention of metabolic disorders …