The regulation of necroptosis and perspectives for the development of new drugs preventing ischemic/reperfusion of cardiac injury
LN Maslov, SV Popov, NV Naryzhnaya… - Apoptosis, 2022 - Springer
In the last 10 years, mortality from acute myocardial infarction (AMI) has not significantly
decreased. This situation is associated with the absence in clinical practice of highly …
decreased. This situation is associated with the absence in clinical practice of highly …
[HTML][HTML] Epigenetic regulation of diverse regulated cell death modalities in cardiovascular disease: insights into necroptosis, pyroptosis, ferroptosis, and cuproptosis
C Chen, J Wang, S Zhang, X Zhu, J Hu, C Liu, L Liu - Redox Biology, 2024 - Elsevier
Cell death constitutes a critical component of the pathophysiology of cardiovascular
diseases. A growing array of non-apoptotic forms of regulated cell death (RCD)—such as …
diseases. A growing array of non-apoptotic forms of regulated cell death (RCD)—such as …
The impact of single nucleotide polymorphism in the long non-coding MEG3 gene on microRNA-182 and microRNA-29 expression levels in the development of breast …
Early-stage detection of BC is a critical factor for effective treatment of the disease and can
increase the survival rate of BC patients. Long non-coding RNAs can act as miRNA decoys …
increase the survival rate of BC patients. Long non-coding RNAs can act as miRNA decoys …
Dasatinib ameliorates thioacetamide-induced liver fibrosis: modulation of miR-378 and miR-17 and their linked Wnt/β-catenin and TGF-β/smads pathways
MA Zaafan, AM Abdelhamid - Journal of enzyme inhibition and …, 2022 - Taylor & Francis
Hepatic stellate cells activation (HSCs) plays a crucial role in the pathogenesis of liver
fibrosis. Specific microRNAs have been suggested to affect the activation of HSCs via …
fibrosis. Specific microRNAs have been suggested to affect the activation of HSCs via …
The hepatoprotective effect of piperine against thioacetamide-induced liver fibrosis in mice: The involvement of miR-17 and TGF-β/smads pathways
AM Abdelhamid, A Selim, MA Zaafan - Frontiers in molecular …, 2021 - frontiersin.org
Liver fibrosis is characterized by a series of events including activation of quiescent hepatic
stellate cells (HSCs) into proinflammatory, contractile, and fibrogenic myofibroblasts, which …
stellate cells (HSCs) into proinflammatory, contractile, and fibrogenic myofibroblasts, which …
Pharmaceutical Therapies for Necroptosis in Myocardial Ischemia–Reperfusion Injury
Y Zhang, Y Zhang, J Zang, Y Li, X Wu - Journal of Cardiovascular …, 2023 - mdpi.com
Cardiovascular disease morbidity/mortality are increasing due to an aging population and
the rising prevalence of diabetes and obesity. Therefore, innovative cardioprotective …
the rising prevalence of diabetes and obesity. Therefore, innovative cardioprotective …
[PDF][PDF] The cardioprotective effect of astaxanthin against isoprenaline-induced myocardial injury in rats: involvement of TLR4/NF-κB signaling pathway.
MA Zaafan, AM Abdelhamid - European Review for Medical & …, 2021 - researchgate.net
OBJECTIVE: Cardiovascular diseases (CVDs) are a major cause of morbidity and mortality
around the world. Nuclear transcription factor kappa B (NF-κB) represents a factor that plays …
around the world. Nuclear transcription factor kappa B (NF-κB) represents a factor that plays …
Response surface optimization of a cardioprotective compound through pharmacosomal drug delivery system: in vivo bioavailability and cardioprotective activity …
Vanillic acid (VA) is a phenolic compound with potential antioxidant activity, which improves
ischemia-induced myocardial degeneration, by reducing oxidative stress; however, it suffers …
ischemia-induced myocardial degeneration, by reducing oxidative stress; however, it suffers …
Implication of miR-122, miR-483, and miR-335 expression levels as potential signatures in HCV-related hepatocellular carcinoma (HCC) in Egyptian patients
AY Elfert, A Salem, AM Abdelhamid… - Frontiers in Molecular …, 2022 - frontiersin.org
Hepatocellular carcinoma (HCC) is the second most common cause of cancer-related
deaths worldwide with chronic hepatitis C virus (HCV) infection as a major risk factor of …
deaths worldwide with chronic hepatitis C virus (HCV) infection as a major risk factor of …
Non-coding RNAs in necroptosis, pyroptosis, and ferroptosis in cardiovascular diseases
Y Cai, Y Zhou, Z Li, P Xia, X ChenFu, A Shi… - Frontiers in …, 2022 - frontiersin.org
Accumulating evidence has proved that non-coding RNAs (ncRNAs) play a critical role in
the genetic programming and gene regulation of cardiovascular diseases (CVDs) …
the genetic programming and gene regulation of cardiovascular diseases (CVDs) …