In spite of the considerable achievements in the field of regenerative medicine in the past
several decades, osteochondral defect regeneration remains a challenging issue among …

This review is intended to give a state of the art description of scaffold-based strategies
utilized in Bone Tissue Engineering. Numerous scaffolds have been tested in the orthopedic …

Repairing articular osteochondral defects present considerable challenges in self‐repair
due to the complex tissue structure and low proliferation of chondrocytes. Conventional …

Successful osteochondral defect repair requires regenerating the subchondral bone whilst
simultaneously promoting the development of an overlying layer of articular cartilage that is …

With the emerging interest in regenerative medicine and tissue engineering, new treatment
modalities being developed for joint disorders including joint surface lesions and articular …

For a successful clinical outcome, periodontal regeneration requires the coordinated
response of multiple soft and hard tissues (periodontal ligament, gingiva, cementum, and …

Much research is currently ongoing into new therapies for cartilage defect repair with new
biomaterials frequently appearing which purport to have significant regenerative capacity …

The design of artificial extracellular matrix (ECM) is important in tissue engineering because
artificial ECM regulates cellular behaviors, including proliferation, survival, migration, and …

Bone is a complex biologic tissue, which is extremely relevant for various physiological
functions, in addition to movement, organ protection, and weight bearing. The repair of …

Biological scaffolds generated from tissue-derived extracellular matrix (ECM) are commonly
used clinically for soft tissue regeneration. Such biomaterials can enhance tissue-specific …