Using phosphoproteomics data to understand cellular signaling: a comprehensive guide to bioinformatics resources
Mass spectrometry-based phosphoproteomics is becoming an essential methodology for the
study of global cellular signaling. Numerous bioinformatics resources are available to …
study of global cellular signaling. Numerous bioinformatics resources are available to …
Protein flexibility in the light of structural alphabets
P Craveur, AP Joseph, J Esque, TJ Narwani… - Frontiers in molecular …, 2015 - frontiersin.org
Protein structures are valuable tools to understand protein function. Nonetheless, proteins
are often considered as rigid macromolecules while their structures exhibit specific flexibility …
are often considered as rigid macromolecules while their structures exhibit specific flexibility …
Ultra-deep tyrosine phosphoproteomics enabled by a phosphotyrosine superbinder
We present a new strategy for systematic identification of phosphotyrosine (pTyr) by affinity
purification mass spectrometry (AP-MS) using a Src homology 2 (SH2)-domain-derived pTyr …
purification mass spectrometry (AP-MS) using a Src homology 2 (SH2)-domain-derived pTyr …
qPTM: an updated database for PTM dynamics in human, mouse, rat and yeast
K Yu, Y Wang, Y Zheng, Z Liu, Q Zhang… - Nucleic Acids …, 2023 - academic.oup.com
Post-translational modifications (PTMs) are critical molecular mechanisms that regulate
protein functions temporally and spatially in various organisms. Since most PTMs are …
protein functions temporally and spatially in various organisms. Since most PTMs are …
CPLM 4.0: an updated database with rich annotations for protein lysine modifications
W Zhang, X Tan, S Lin, Y Gou, C Han… - Nucleic Acids …, 2022 - academic.oup.com
Here, we reported the compendium of protein lysine modifications (CPLM 4.0, http://cplm.
biocuckoo. cn/), a data resource for various post-translational modifications (PTMs) …
biocuckoo. cn/), a data resource for various post-translational modifications (PTMs) …
Clinically relevant post-translational modification analyses—maturing workflows and bioinformatics tools
Post-translational modifications (PTMs) can occur soon after translation or at any stage in
the lifecycle of a given protein, and they may help regulate protein folding, stability, cellular …
the lifecycle of a given protein, and they may help regulate protein folding, stability, cellular …
SUMO: A Swiss army knife for eukaryotic topoisomerases
Topoisomerases play crucial roles in DNA metabolism that include replication, transcription,
recombination, and chromatin structure by manipulating DNA structures arising in double …
recombination, and chromatin structure by manipulating DNA structures arising in double …
qPhos: a database of protein phosphorylation dynamics in humans
K Yu, Q Zhang, Z Liu, Q Zhao, X Zhang… - Nucleic acids …, 2019 - academic.oup.com
Temporal and spatial protein phosphorylation dynamically orchestrates a broad spectrum of
biological processes and plays various physiological and pathological roles in diseases and …
biological processes and plays various physiological and pathological roles in diseases and …
Quantitative real-time analysis of differentially expressed genes in peripheral blood samples of hypertension patients
Hypertension (HTN) is considered one of the most important and well-established reasons
for cardiovascular abnormalities, strokes, and premature mortality globally. This study was …
for cardiovascular abnormalities, strokes, and premature mortality globally. This study was …
[HTML][HTML] Aberrant phase separation is a common killing strategy of positively charged peptides in biology and human disease
Positively charged repeat peptides are emerging as key players in neurodegenerative
diseases. These peptides can perturb diverse cellular pathways but a unifying framework for …
diseases. These peptides can perturb diverse cellular pathways but a unifying framework for …