Therapeutic repair for spinal cord injury: combinatory approaches to address a multifaceted problem
JM Griffin, F Bradke - EMBO molecular medicine, 2020 - embopress.org
The recent years saw the advent of promising preclinical strategies that combat the
devastating effects of a spinal cord injury (SCI) that are progressing towards clinical trials …
devastating effects of a spinal cord injury (SCI) that are progressing towards clinical trials …
Regenerative therapies for spinal cord injury
Spinal cord injury (SCI) is a serious problem that primarily affects younger and middle-aged
adults at its onset. To date, no effective regenerative treatment has been developed. Over …
adults at its onset. To date, no effective regenerative treatment has been developed. Over …
Stem cell therapy for spinal cord injury
L Huang, C Fu, F Xiong, C He, Q Wei - Cell transplantation, 2021 - journals.sagepub.com
Traumatic spinal cord injury (SCI) results in direct and indirect damage to neural tissues,
which results in motor and sensory dysfunction, dystonia, and pathological reflex that …
which results in motor and sensory dysfunction, dystonia, and pathological reflex that …
Regenerative therapies for central nervous system diseases: a biomaterials approach
The central nervous system (CNS) has a limited capacity to spontaneously regenerate
following traumatic injury or disease, requiring innovative strategies to promote tissue and …
following traumatic injury or disease, requiring innovative strategies to promote tissue and …
Three-dimensional aligned nanofibers-hydrogel scaffold for controlled non-viral drug/gene delivery to direct axon regeneration in spinal cord injury treatment
Spinal cord injuries (SCI) often lead to persistent neurological dysfunction due to failure in
axon regeneration. Unfortunately, currently established treatments, such as direct drug …
axon regeneration. Unfortunately, currently established treatments, such as direct drug …
Combinatorial therapies after spinal cord injury: how can biomaterials help?
T Führmann, PN Anandakumaran… - Advanced healthcare …, 2017 - Wiley Online Library
Traumatic spinal cord injury (SCI) results in an immediate loss of motor and sensory function
below the injury site and is associated with a poor prognosis. The inhibitory environment that …
below the injury site and is associated with a poor prognosis. The inhibitory environment that …
Injectable hydrogel materials for spinal cord regeneration: a review
D Macaya, M Spector - Biomedical materials, 2012 - iopscience.iop.org
Spinal cord injury (SCI) presents a complex regenerative problem due to the multiple facets
of growth inhibition that occur following trauma to the cord parenchyma and stroma …
of growth inhibition that occur following trauma to the cord parenchyma and stroma …
Current concepts of biomaterial scaffolds and regenerative therapy for spinal cord injury
Spinal cord injury (SCI) is a catastrophic condition associated with significant neurological
deficit and social and financial burdens. It is currently being managed symptomatically, with …
deficit and social and financial burdens. It is currently being managed symptomatically, with …
Advances in fibrin-based materials in wound repair: a review
IS Bayer - Molecules, 2022 - mdpi.com
The first bioprocess that occurs in response to wounding is the deterrence of local
hemorrhage. This is accomplished by platelet aggregation and initiation of the hemostasis …
hemorrhage. This is accomplished by platelet aggregation and initiation of the hemostasis …
Neural stem/progenitor cell transplantation for spinal cord injury treatment; A systematic review and meta-analysis
Despite the vast improvements of cell therapy in spinal cord injury treatment, no optimum
protocol has been developed for application of neural stem/progenitor cells. In this regard …
protocol has been developed for application of neural stem/progenitor cells. In this regard …