Designer drugs: mechanism of action and adverse effects

D Luethi, ME Liechti - Archives of toxicology, 2020 - Springer
Psychoactive substances with chemical structures or pharmacological profiles that are
similar to traditional drugs of abuse continue to emerge on the recreational drug market …

A systematic review of adverse events arising from the use of synthetic cannabinoids and their associated treatment

RJ Tait, D Caldicott, D Mountain, SL Hill… - Clinical …, 2016 - Taylor & Francis
Abstract Context: Synthetic cannabinoids (SCs) such as “Spice”,“K2”, etc. are widely
available via the internet despite increasing legal restrictions. Currently, the prevalence of …

[HTML][HTML] “Zombie” outbreak caused by the synthetic cannabinoid AMB-FUBINACA in New York

AJ Adams, SD Banister, L Irizarry, J Trecki… - New England journal …, 2017 - Mass Medical Soc
Background New psychoactive substances constitute a growing and dynamic class of
abused drugs in the United States. On July 12, 2016, a synthetic cannabinoid caused mass …

Rapid biosensor development using plant hormone receptors as reprogrammable scaffolds

J Beltrán, PJ Steiner, M Bedewitz, S Wei… - Nature …, 2022 - nature.com
A general method to generate biosensors for user-defined molecules could provide
detection tools for a wide range of biological applications. Here, we describe an approach …

Mechanisms of cannabidiol (CBD) in cancer treatment: A review

CG Heider, SA Itenberg, J Rao, H Ma, X Wu - Biology, 2022 - mdpi.com
Simple Summary Emerging evidence suggests positive outcomes from the use of CBD as a
cancer treatment. CBD can relieve cancer pain and ease the side effects of chemotherapy; …

Pharmacology of Valinate and tert-Leucinate Synthetic Cannabinoids 5F-AMBICA, 5F-AMB, 5F-ADB, AMB-FUBINACA, MDMB-FUBINACA, MDMB-CHMICA, and …

SD Banister, M Longworth, R Kevin… - ACS Chemical …, 2016 - ACS Publications
Indole and indazole synthetic cannabinoids (SCs) featuring l-valinate or l-tert-leucinate
pendant group have recently emerged as prevalent recreational drugs, and their use has …

Synthesis and in Vitro Cannabinoid Receptor 1 Activity of Recently Detected Synthetic Cannabinoids 4F-MDMB-BICA, 5F-MPP-PICA, MMB-4en-PICA, CUMYL …

A Cannaert, E Sparkes, E Pike, JL Luo… - ACS Chemical …, 2020 - ACS Publications
Synthetic cannabinoid receptor agonists (SCRAs) are an evolving class of new psychoactive
substances (NPS) with structurally diverse compounds emerging each year. Due to the rapid …

Synthetic cathinone and cannabinoid designer drugs pose a major risk for public health

AM Weinstein, P Rosca, L Fattore… - Frontiers in psychiatry, 2017 - frontiersin.org
As part of an increasing worldwide use of designer drugs, recent use of compounds
containing cathinones and synthetic cannabinoids is especially prevalent. Here, we …

Reports of adverse events associated with use of novel psychoactive substances, 2013–2016: a review

BK Logan, ALA Mohr, M Friscia… - Journal of Analytical …, 2017 - academic.oup.com
Novel psychoactive substances (NPS) represent significant analytical and interpretive
challenges to forensic and clinical toxicologists. Timely access to case reports and reports of …

[HTML][HTML] E-cigarettes—an unintended illicit drug delivery system

AK Breitbarth, J Morgan, AL Jones - Drug and alcohol dependence, 2018 - Elsevier
Since the introduction of electronic cigarettes (e-cigarettes) in 2003, the technology has
advanced allowing for greater user modifications, with users now able to control voltage …