Considering the high mortality rate encountered in lung cancer, there is a strong need to
explore new biomarkers for early diagnosis and also improved therapeutic targets to …

The development of drug resistance continues to be a dominant hindrance toward curative
cancer treatment. Overexpression of a wide-spectrum of ATP-dependent efflux pumps, and …

The ATP binding-cassette superfamily corresponds the mostly transmembrane transporters
family found in humans. These proteins actively transport endogenous and exogenous …

MicroRNAs (miRNAs) are small non-coding RNAs (18–24 nucleotides) that play significant
roles in cell proliferation, development, invasion, cancer development, cancer progression …

Oral squamous cell carcinoma (OSCC) is among the most commonly diagnosed
malignancies in the world. Patients with OSCC often develop treatment resistance, resulting …

The discovery of microRNAs (miRNAs) 20 years ago has advocated a new era of “small
molecular genetics.” About 2000 miRNAs are present that regulate one third of the genome …

Background We previously reported an inverse relationship between B cell-specific Moloney
murine leukemia virus integration site 1 (Bmi-1) and Raf kinase inhibitory protein (RKIP) …

Objective The chemo-preventative and therapeutic properties of selenium nanoparticles
(SeNPs) have been documented over recent decades and suggest the potential uses of …

Circulating microRNAs (miRNAs) have the potential to become reliable and noninvasive
biomarkers for ovarian cancer (OC) diagnosis; however, the conventional miRNAs detection …

Background Chemotherapy based on paclitaxel (PTX) is the standard treatment for a range
of cancers, including triple-negative breast cancer (TNBC), but the increasing development …