As an anti-inflammatory alkaloid, nicotine plays dual roles in treating diseases. Here we
reviewed the anti-inflammatory and pro-inflammatory effects of nicotine on inflammatory …

Inflammatory bowel disease (IBD) encompasses a set of chronic inflammatory conditions,
namely Crohn's disease and ulcerative colitis. Despite all advances in the management of …

The “leaky gut” syndrome describes a damaged (leaky) intestinal mucosa and is considered
a serious contributor to numerous chronic diseases. Chronic inflammatory bowel diseases …

Inflammatory bowel disease causes a major burden to patients and healthcare systems,
raising the need to develop effective therapies. Technological advances in cell culture, allied …

Carboxymethyl cellulose use in industry is ubiquitous. Though it is recognized as safe by the
EFSA and FDA, newer works have raised concerns related to its safety, as in vivo studies …

The human colorectal adenocarcinoma cell line Caco-2, widely used for studying intestinal
drug permeability, is typically grown on permeable filter supports and matures in 21 days …

Inflammatory bowel disease (IBD) refers to chronic intestinal immune-mediated diseases
including two main disease manifestations: ulcerative colitis (UC) and Crohn's disease (CD) …

As a vitro absorption model, the Caco-2 cells originate from a human colon
adenocarcinomas and can differentiate into a cell layer with enterocyte-like features. The …

Previously established immune-responsive co-culture models with macrophages have
limitations due to the dedifferentiation of macrophages in long-term cultures. This study is …

The compositional balance of intestinal microbiota plays an important role in maintaining
homeostasis. This study aimed to investigate the intestinal flora of hepatitis B virus …