Optical microscopy has emerged as a key driver of fundamental research since it provides
the ability to probe into imperceptible structures in the biomedical world. For the detailed …

Light-sheet fluorescence microscopy (LSFM) methods collectively represent the major
breakthrough in developmental bio-imaging of living multicellular organisms. They are …

Light-sheet fluorescent microscopy has become the leading technique for in vivo imaging in
the fields of disease, medicine, and cell biology research. However, designing proper …

The introduction of light sheet fluorescence microscopy (LSFM) has overcome the
challenges in conventional optical microscopy. Among the recent breakthroughs in …

Imaging living organisms at high spatial resolution requires effective and innocuous
immobilization. Long-term imaging places further demands on sample mounting with …

Diffusion is a major molecular transport mechanism in biological systems. Quantifying
direction-dependent (ie, anisotropic) diffusion is vitally important to depicting how the three …

While fluorescence microscopy has proven to be an exceedingly useful tool in bioscience, it
is difficult to offer simultaneous high resolution, fast speed, large volume, and good …

Fluorescence recovery after photobleaching (FRAP) has emerged as one of the most widely
utilized techniques to quantify binding and diffusion kinetics of biomolecules in biophysics …

Macrocyclic lactones (MLs) are widely used drugs to treat and prevent parasitic nematode
infections. In many nematode species including a major pathogen of foals, Parascaris …

Advanced fluorescence techniques, commonly known as the F-techniques, measure the
kinetics and the interactions of biomolecules with high sensitivity and spatiotemporal …