Peptide–nanoparticle conjugates: a next generation of diagnostic and therapeutic platforms?
Peptide–nanoparticle conjugates (PNCs) have recently emerged as a versatile tool for
biomedical applications. Synergism between the two promising classes of materials allows …
biomedical applications. Synergism between the two promising classes of materials allows …
[HTML][HTML] Overview of the detection methods for equilibrium dissociation constant KD of drug-receptor interaction
W Ma, L Yang, L He - Journal of pharmaceutical analysis, 2018 - Elsevier
Drug-receptor interaction plays an important role in a series of biological effects, such as cell
proliferation, immune response, tumor metastasis, and drug delivery. Therefore, the …
proliferation, immune response, tumor metastasis, and drug delivery. Therefore, the …
Bispecific Antibodies Produced via Chemical Site-Specific Conjugation Technology: AJICAP Second-Generation
T Fujii, K Ito, K Takahashi, T Aoki… - ACS Medicinal …, 2023 - ACS Publications
Bispecific antibodies (BisAbs) are biotherapeutics that amalgamate the specificities of two
distinct antibodies into one molecule, however, their engineering requires genetic …
distinct antibodies into one molecule, however, their engineering requires genetic …
Enhanced EGFR targeting activity of plasmonic nanostructures with engineered GE11 peptide
F Biscaglia, S Rajendran, P Conflitti… - Advanced …, 2017 - Wiley Online Library
Plasmonic nanostructures show important properties for biotechnological applications, but
they have to be guided on the target for exploiting their potentialities. Antibodies are the …
they have to be guided on the target for exploiting their potentialities. Antibodies are the …
Novel perspective for protein–drug interaction analysis: atomic force microscope
H Sun, J Wang - Analyst, 2023 - pubs.rsc.org
Proteins are major drug targets, and drug–target interaction identification and analysis are
important factors for drug discovery. Atomic force microscopy (AFM) is a powerful tool …
important factors for drug discovery. Atomic force microscopy (AFM) is a powerful tool …
Identification of potential targets of the curcumin analog CCA-1.1 for glioblastoma treatment: integrated computational analysis and in vitro study
The treatment of glioblastoma multiforme (GBM) is challenging owing to its localization in the
brain, the limited capacity of brain cells to repair, resistance to conventional therapy, and its …
brain, the limited capacity of brain cells to repair, resistance to conventional therapy, and its …
Biosensor-based active ingredients recognition system for screening STAT3 ligands from medical herbs
L Chen, D Lv, X Chen, M Liu, D Wang, Y Liu… - Analytical …, 2018 - ACS Publications
A surface plasmon resonance (SPR) biosensor-based active ingredients recognition system
(SPR-AIRS) was developed, validated, and applied to screen signal transducer and …
(SPR-AIRS) was developed, validated, and applied to screen signal transducer and …
Characterization of EGF-guided MDA-MB-231 cell chemotaxis in vitro using a physiological and highly sensitive assay system
V Biswenger, N Baumann, J Jürschick, M Häckl… - PloS one, 2018 - journals.plos.org
Chemotactic cell migration is a central mechanism during cancer cell invasion and hence
metastasis. In order to mimic in vivo conditions, we used a three-dimensional hydrogel …
metastasis. In order to mimic in vivo conditions, we used a three-dimensional hydrogel …
Biodistribution and activity of EGFR targeted polymeric micelles delivering a new inhibitor of DNA repair to Orthotopic colorectal Cancer xenografts with metastasis
IM de Paiva, MR Vakili, AH Soleimani… - Molecular …, 2022 - ACS Publications
The disruption of polynucleotide kinase/phosphatase (PNKP) in colorectal cancer (CRC)
cells deficient in phosphatase and tensin homolog (PTEN) is expected to lead to the loss of …
cells deficient in phosphatase and tensin homolog (PTEN) is expected to lead to the loss of …
Evaluating the therapeutic efficacy of nano-drugs targeting epidermal growth factor receptor
J Zhao, S Li, X Pang, Y Shan - Chemical Communications, 2022 - pubs.rsc.org
Epidermal growth factor receptor (EGFR) targeted nano-drugs facilitate effective diagnosis
and treatment of cancer. Herein, the therapeutic efficacy of nano-drugs targeting EGFR was …
and treatment of cancer. Herein, the therapeutic efficacy of nano-drugs targeting EGFR was …