Progress in construction of mouse models to investigate the pathogenesis and immune therapy of human hematological malignancy

Y Lang, Y Lyu, Y Tan, Z Hu - Frontiers in Immunology, 2023 - frontiersin.org
Hematological malignancy is a disease arisen by complicate reasons that seriously
endangers human health. The research on its pathogenesis and therapies depends on the …

Genetic abnormalities in extramedullary multiple myeloma

R McAvera, J Quinn, P Murphy, S Glavey - International Journal of …, 2023 - mdpi.com
Extramedullary multiple myeloma (or extramedullary disease, EMD) is an aggressive form of
multiple myeloma (MM) that occurs when malignant plasma cells become independent of …

Novel myeloma patient-derived xenograft models unveil the potency of anlotinib to overcome bortezomib resistance

Y Yue, Y Cao, X Mao, F Wang, P Fan, L Qian… - Frontiers in …, 2022 - frontiersin.org
Multiple myeloma (MM) remains a common hematologic malignancy with a 10-year survival
rate below 50%, which is largely due to disease relapse and resistance. The lack of a simple …

The apparent diffusion coefficient of diffusion-weighted whole-body magnetic resonance imaging affects the survival of multiple myeloma independently

B Zhang, B Bian, Y Zhang, L Zhang, R Zhang… - Frontiers in …, 2022 - frontiersin.org
Background Diffusion-weighted whole-body MRI (DW-MRI) is increasingly used to evaluate
bone diseases of multiple myeloma (MM), but there is lack of quantitative indicator for DW …

Sharing resources to advance translational research

KM Hooper, J Hmeljak - Disease Models & Mechanisms, 2022 - journals.biologists.com
The publication of Resource articles is essential for the dissemination of novel, or
substantially enhanced, tools, techniques, disease models, datasets and resources. By …

Uso de tumoroides y" orthoxenografts" para la identificación de nuevas terapias en cáncer de colon con inestabilidad de microsatélites

JF Martín Tejera - 2022 - diposit.ub.edu
[spa] En las últimas décadas se ha producido una tendencia de estabilización en la
mortalidad del cáncer colorrectal (CCR) atribuido, en mayor parte, a la disponibilidad de …