Isatin derivatives and their anti-bacterial activities
H Guo - European Journal of Medicinal Chemistry, 2019 - Elsevier
Bacterial infections are account for the majority of hospital-acquired and community-
acquired infections. The emergency and widespread of drug-resistant pathogens has further …
acquired infections. The emergency and widespread of drug-resistant pathogens has further …
Biochemical and pharmacological characterization of isatin and its derivatives: from structure to activity
Abstract Isatin, k1H-indole-2, 3-dione, kis a heterocyclic compound of significant importance
in medicinal chemistry. It is a synthetically versatile molecule, ka precursor for a large …
in medicinal chemistry. It is a synthetically versatile molecule, ka precursor for a large …
Bis-isatin hydrazones with novel linkers: Synthesis and biological evaluation as cytotoxic agents
HS Ibrahim, SM Abou-Seri, NSM Ismail… - European Journal of …, 2016 - Elsevier
Many bis-isatins and isatins with hydrazide extension were reported to have a potential anti-
proliferative effects against different cancer cell lines and cancer targets. In this study, four …
proliferative effects against different cancer cell lines and cancer targets. In this study, four …
[HTML][HTML] Synthesis, antimicrobial, anticancer, antiviral evaluation and QSAR studies of 4-(1-aryl-2-oxo-1, 2-dihydro-indol-3-ylideneamino)-N-substituted benzene …
M Kumar, K Ramasamy, V Mani, RK Mishra… - Arabian Journal of …, 2014 - Elsevier
Abstract A series of 4-(1-aryl-2-oxo-1, 2-dihydro-indol-3-ylideneamino)-N-substituted
benzenesulfonamide derivatives (1–32) was synthesized and evaluated for its in vitro …
benzenesulfonamide derivatives (1–32) was synthesized and evaluated for its in vitro …
[HTML][HTML] Study on the interaction between isatin-β-thiosemicarbazone and calf thymus DNA by spectroscopic techniques
P Pakravan, S Masoudian - Iranian journal of pharmaceutical …, 2015 - ncbi.nlm.nih.gov
The interaction between isatin-β-thiosemicarbazone (IBT) and calf thymus DNA (CT-DNA)
was investigated in physiological buffer (pH 7.4) using Neutral Red (NR) dye as a spectral …
was investigated in physiological buffer (pH 7.4) using Neutral Red (NR) dye as a spectral …
Design, synthesis and evaluation of a series of 1, 5‐Diaryl‐1, 2, 3‐triazole‐4‐carbohydrazones as inhibitors of the YAP‐TAZ/TEAD complex
F Gibault, M Sturbaut, M Coevoet, M Pugnière… - …, 2021 - Wiley Online Library
Starting from our previously reported hit, a series of 1, 5‐diaryl‐1, 2, 3‐triazole‐4‐
carbohydrazones were synthesized and evaluated as inhibitors of the YAP/TAZ‐TEAD …
carbohydrazones were synthesized and evaluated as inhibitors of the YAP/TAZ‐TEAD …
[PDF][PDF] Bis-Schiff bases of isatin derivatives synthesis, and their biological activities: a review
Isatin is a heterocyclic molecule that belongs to one of the most important classes of organic
compounds known as indolines. Isatin, isatin analogs, and their Schiff bases have recently …
compounds known as indolines. Isatin, isatin analogs, and their Schiff bases have recently …
Synthesis, characterization and biocidal activity of some transition metal (II) complexes with isatin salicylaldehyde acyldihydrazones
Cobalt (II), nickel (II), copper (II), zinc (II) and cadmium (II) complexes with two new
unsymmetrical ligands, isatin salicylaldehyde oxalic acid dihydrazide (isodh) and isatin …
unsymmetrical ligands, isatin salicylaldehyde oxalic acid dihydrazide (isodh) and isatin …
Isatin nitro-derivatives redox behaviour
SCB Oliveira, IPG Fernandes, BV Silva, AC Pinto… - Journal of …, 2013 - Elsevier
Isatin derivatives possess a broad pharmacological profile and clinical applications, and the
electrochemical behaviour of isatin-3-hydrazone, 7-methylisatin-3-hydrazone, isatin-3 …
electrochemical behaviour of isatin-3-hydrazone, 7-methylisatin-3-hydrazone, isatin-3 …
Molecular aspects on the interaction of isatin-3-isonicotinylhydrazone to deoxyribonucleic acid: model for intercalative drug-DNA binding
Isatin-3-isonicotinylhydrazone was synthesized and characterized. The interaction of native
calf thymus DNA with isatin-3-isonicotinylhydrazone (IINH) in 10 mM Tris–HCl aqueous …
calf thymus DNA with isatin-3-isonicotinylhydrazone (IINH) in 10 mM Tris–HCl aqueous …