Isatin derivatives and their anti-bacterial activities

H Guo - European Journal of Medicinal Chemistry, 2019 - Elsevier
Bacterial infections are account for the majority of hospital-acquired and community-
acquired infections. The emergency and widespread of drug-resistant pathogens has further …

Biochemical and pharmacological characterization of isatin and its derivatives: from structure to activity

P Pakravan, S Kashanian, MM Khodaei… - Pharmacological …, 2013 - Springer
Abstract Isatin, k1H-indole-2, 3-dione, kis a heterocyclic compound of significant importance
in medicinal chemistry. It is a synthetically versatile molecule, ka precursor for a large …

Bis-isatin hydrazones with novel linkers: Synthesis and biological evaluation as cytotoxic agents

HS Ibrahim, SM Abou-Seri, NSM Ismail… - European Journal of …, 2016 - Elsevier
Many bis-isatins and isatins with hydrazide extension were reported to have a potential anti-
proliferative effects against different cancer cell lines and cancer targets. In this study, four …

[HTML][HTML] Synthesis, antimicrobial, anticancer, antiviral evaluation and QSAR studies of 4-(1-aryl-2-oxo-1, 2-dihydro-indol-3-ylideneamino)-N-substituted benzene …

M Kumar, K Ramasamy, V Mani, RK Mishra… - Arabian Journal of …, 2014 - Elsevier
Abstract A series of 4-(1-aryl-2-oxo-1, 2-dihydro-indol-3-ylideneamino)-N-substituted
benzenesulfonamide derivatives (1–32) was synthesized and evaluated for its in vitro …

[HTML][HTML] Study on the interaction between isatin-β-thiosemicarbazone and calf thymus DNA by spectroscopic techniques

P Pakravan, S Masoudian - Iranian journal of pharmaceutical …, 2015 - ncbi.nlm.nih.gov
The interaction between isatin-β-thiosemicarbazone (IBT) and calf thymus DNA (CT-DNA)
was investigated in physiological buffer (pH 7.4) using Neutral Red (NR) dye as a spectral …

Design, synthesis and evaluation of a series of 1, 5‐Diaryl‐1, 2, 3‐triazole‐4‐carbohydrazones as inhibitors of the YAP‐TAZ/TEAD complex

F Gibault, M Sturbaut, M Coevoet, M Pugnière… - …, 2021 - Wiley Online Library
Starting from our previously reported hit, a series of 1, 5‐diaryl‐1, 2, 3‐triazole‐4‐
carbohydrazones were synthesized and evaluated as inhibitors of the YAP/TAZ‐TEAD …

[PDF][PDF] Bis-Schiff bases of isatin derivatives synthesis, and their biological activities: a review

MMJ Al-Mudhafar, TNA Omar, SL Abdulhadi - Al Mustansiriyah Journal of …, 2022 - iasj.net
Isatin is a heterocyclic molecule that belongs to one of the most important classes of organic
compounds known as indolines. Isatin, isatin analogs, and their Schiff bases have recently …

Synthesis, characterization and biocidal activity of some transition metal (II) complexes with isatin salicylaldehyde acyldihydrazones

VP Singh, S Singh, DP Singh - Journal of enzyme inhibition and …, 2012 - Taylor & Francis
Cobalt (II), nickel (II), copper (II), zinc (II) and cadmium (II) complexes with two new
unsymmetrical ligands, isatin salicylaldehyde oxalic acid dihydrazide (isodh) and isatin …

Isatin nitro-derivatives redox behaviour

SCB Oliveira, IPG Fernandes, BV Silva, AC Pinto… - Journal of …, 2013 - Elsevier
Isatin derivatives possess a broad pharmacological profile and clinical applications, and the
electrochemical behaviour of isatin-3-hydrazone, 7-methylisatin-3-hydrazone, isatin-3 …

Molecular aspects on the interaction of isatin-3-isonicotinylhydrazone to deoxyribonucleic acid: model for intercalative drug-DNA binding

S Kashanian, MM Khodaei, P Pakravan… - Molecular biology reports, 2012 - Springer
Isatin-3-isonicotinylhydrazone was synthesized and characterized. The interaction of native
calf thymus DNA with isatin-3-isonicotinylhydrazone (IINH) in 10 mM Tris–HCl aqueous …