[HTML][HTML] Critical role of interleukin (IL)-17 in inflammatory and immune disorders: An updated review of the evidence focusing in controversies
Abstract Interleukin 17 (IL-17) is a proinflammatory cytokine that has been the focus of
intensive research because of its crucial role in the pathogenesis of different diseases …
intensive research because of its crucial role in the pathogenesis of different diseases …
Current concepts and advances in graft-versus-host disease immunology
Worldwide, each year over 30,000 patients undergo an allogeneic hema-topoietic stem cell
transplantation with the intent to cure high-risk hematologic malignancy, immunodeficiency …
transplantation with the intent to cure high-risk hematologic malignancy, immunodeficiency …
Intestinal microbiota controls graft-versus-host disease independent of donor-host genetic disparity
M Koyama, DS Hippe, S Srinivasan, SC Proll… - Immunity, 2023 - cell.com
Acute graft-versus-host disease (aGVHD) remains a major limitation of allogeneic stem cell
transplantation (SCT), and severe intestinal manifestation is the major cause of early …
transplantation (SCT), and severe intestinal manifestation is the major cause of early …
Gut microbiota injury in allogeneic haematopoietic stem cell transplantation
Y Shono, MRM van den Brink - Nature Reviews Cancer, 2018 - nature.com
Allogeneic haematopoietic stem cell transplantation (allo-HSCT) is considered to be the
strongest curative immunotherapy for various malignancies (primarily, but not limited to …
strongest curative immunotherapy for various malignancies (primarily, but not limited to …
[HTML][HTML] MHC class II antigen presentation by the intestinal epithelium initiates graft-versus-host disease and is influenced by the microbiota
Graft-versus-host disease (GVHD) in the gastrointestinal (GI) tract is the principal
determinant of lethality following allogeneic bone marrow transplantation (BMT). Here, we …
determinant of lethality following allogeneic bone marrow transplantation (BMT). Here, we …
Stool microbiota at neutrophil recovery is predictive for severe acute graft vs host disease after hematopoietic cell transplantation
Background Graft-versus-host disease (GVHD) is common after allogeneic hematopoietic
cell transplantation (HCT). Risk for death from GVHD has been associated with low bacterial …
cell transplantation (HCT). Risk for death from GVHD has been associated with low bacterial …
Cytokines and costimulation in acute graft-versus-host disease
GR Hill, M Koyama - Blood, The Journal of the American …, 2020 - ashpublications.org
Allogeneic hematopoietic stem cell transplantation (alloSCT) is an important curative
therapy for high-risk hematological malignancies, but the development of severe and/or …
therapy for high-risk hematological malignancies, but the development of severe and/or …
The primacy of gastrointestinal tract antigen-presenting cells in lethal graft-versus-host disease
M Koyama, GR Hill - Blood, The Journal of the American …, 2019 - ashpublications.org
Allogeneic stem cell transplantation is a cornerstone of curative therapy for high-risk and/or
advanced hematological malignancies but remains limited by graft-versus-host disease …
advanced hematological malignancies but remains limited by graft-versus-host disease …
The gut microbiota and graft-versus-host disease
DN Fredricks - The Journal of clinical investigation, 2019 - Am Soc Clin Investig
Graft-versus-host disease (GvHD) is a common complication of hematopoietic cell
transplantation that negatively impacts quality of life in recipients and can be fatal. Animal …
transplantation that negatively impacts quality of life in recipients and can be fatal. Animal …
From osteoimmunology to osteomicrobiology: how the microbiota and the immune system regulate bone
E Hsu, R Pacifici - Calcified tissue international, 2018 - Springer
Osteomicrobiology refers to the role of microbiota in bone health and the mechanisms by
which the microbiota regulates post-natal skeletal development, bone aging, and pathologic …
which the microbiota regulates post-natal skeletal development, bone aging, and pathologic …