Antipsychotics: mechanisms underlying clinical response and side-effects and novel treatment approaches based on pathophysiology

SJ Kaar, S Natesan, R Mccutcheon, OD Howes - Neuropharmacology, 2020 - Elsevier
Antipsychotic drugs are central to the treatment of schizophrenia and other psychotic
disorders but are ineffective for some patients and associated with side-effects and …

A systematic review of factors influencing adherence to antipsychotic medication in schizophrenia-spectrum disorders

KV Sendt, DK Tracy, S Bhattacharyya - Psychiatry research, 2015 - Elsevier
Adherence to antipsychotics improves outcome in schizophrenia. There is a lack of
consensus on which factors most influence adherence behaviour and methodological …

Psychiatric symptoms and quality of life in schizophrenia: a meta-analysis

SM Eack, CE Newhill - Schizophrenia bulletin, 2007 - academic.oup.com
Quality of life (QoL) has been recognized as an important outcome of schizophrenia
treatment, yet the determinants of QoL for individuals with schizophrenia are not well known …

Olanzapine versus other atypical antipsychotics for schizophrenia

K Komossa, C Rummel‐Kluge… - Cochrane Database …, 2010 - cochranelibrary.com
Background In many countries of the industrialised world second generation (" atypical")
antipsychotics have become the first line drug treatment for people with schizophrenia. The …

Quality of life as patient-reported outcomes: principles of assessment

M Bullinger, J Quitmann - Dialogues in clinical neuroscience, 2014 - Taylor & Francis
Assessing quality of life (QoL) as a patient-reported outcome in adult psychiatry poses
challenges in terms of concepts, methods, and applications in research and practice. This …

Impact of present and past antipsychotic side effects on attitude toward typical antipsychotic treatment and adherence

M Lambert, P Conus, P Eide, R Mass, A Karow… - European …, 2004 - cambridge.org
Objective (1) determine which antipsychotic side effects (SE) schizophrenic patients
consider the most distressing during treatment with typical antipsychotics,(2) measure the …

Self-stigma and its relationship with insight, demoralization, and clinical outcome among people with schizophrenia spectrum disorders

M Cavelti, S Kvrgic, EM Beck, N Rüsch… - Comprehensive psychiatry, 2012 - Elsevier
BACKGROUND: Paradoxically, insight is associated with positive outcomes, such as better
treatment adherence and recovery, and negative outcomes, such as depression …

Improvement of cognitive functions in chronic schizophrenic patients by recombinant human erythropoietin

H Ehrenreich, D Hinze-Selch, S Stawicki, C Aust… - Molecular …, 2007 - nature.com
Schizophrenia is increasingly recognized as a neurodevelopmental disease with an
additional degenerative component, comprising cognitive decline and loss of cortical gray …

Internalized stigma among people with schizophrenia: Relationship with socio-demographic, clinical and medication-related features

S Barlati, D Morena, G Nibbio, P Cacciani… - Schizophrenia …, 2022 - Elsevier
Background People with schizophrenia are at high risk of suffering from stigma and
internalizing it. Recently, a better understanding of the stigma process has shifted the …

Quality of life in schizophrenic patients

J Bobes, MP Garcia-Portilla, MT Bascaran… - Dialogues in clinical …, 2007 - Taylor & Francis
In the last decades, there has been increased interest in the field of quality of life in mental
disorders in general, and particularly in schizophrenia. In addition, the appearance of the …