Small RNAs regulate a wide variety of biological processes by repressing the expression of
target genes at the transcriptional and post-transcriptional levels. To achieve these …

MicroRNAs (miRNAs) regulate the expression of most genes in animals, but we are only
now beginning to understand how they are generated, assembled into functional complexes …

RNA binding proteins that act at the post-transcriptional level display a richness of
mechanisms to modulate the transcriptional output and respond to changing cellular …

The insulin-like growth factor-2 mRNA-binding proteins 1, 2, and 3 (IGF2BP1, IGF2BP2,
IGF2BP3) belong to a conserved family of RNA-binding, oncofetal proteins. Several studies …

The IGF2 mRNA-binding protein 1 (IGF2BP1) is a non-catalytic post-transcriptional
enhancer of tumor growth upregulated and associated with adverse prognosis in solid …

In the past decade, microRNAs (miRNAs) have been uncovered as key regulators of gene
expression at the post-transcriptional level. The ancient origin of miRNAs, their dramatic …

The microRNA (miRNA)“sponge” method was introduced three years ago as a means to
create continuous miRNA loss of function in cell lines and transgenic organisms. Sponge …

Motivation: Experimental evidence has accumulated showing that microRNA (miRNA)
binding sites within protein coding sequences (CDSs) are functional in controlling gene …

Simple Summary RNA-binding proteins (RBPs) play central roles in regulating
posttranscriptional expression of genes. Many of them are known to be deregulated in a …

The post-transcriptional control of gene expression mediated by RNA-binding proteins
(RBPs), long non-coding RNAs (lncRNAs) as well as miRNAs is essential to determine …