Affibody molecules as targeting vectors for PET imaging
V Tolmachev, A Orlova - Cancers, 2020 - mdpi.com
Affibody molecules are small (58 amino acids) engineered scaffold proteins that can be
selected to bind to a large variety of proteins with a high affinity. Their small size and high …
selected to bind to a large variety of proteins with a high affinity. Their small size and high …
PET/fluorescence imaging: An overview of the chemical strategies to build dual imaging tools
J Ariztia, K Solmont, NP Moïse, S Specklin… - Bioconjugate …, 2022 - ACS Publications
Molecular imaging is a biomedical research discipline that has quickly emerged to afford the
observation, characterization, monitoring, and quantification of biomarkers and biological …
observation, characterization, monitoring, and quantification of biomarkers and biological …
Radiolabeling Diaminosarcophagine with Cyclotron-Produced Cobalt-55 and [55Co]Co-NT-Sarcage as a Proof of Concept in a Murine Xenograft Model
W Lin, GO Fonseca Cabrera… - Bioconjugate …, 2024 - ACS Publications
Cobalt–sarcophagine complexes exhibit high kinetic inertness under various stringent
conditions, but there is limited literature on radiolabeling and in vivo positron emission …
conditions, but there is limited literature on radiolabeling and in vivo positron emission …
66Ga-PET-imaging of GRPR-expression in prostate cancer: production and characterization of [66Ga]Ga-NOTA-PEG2-RM26
Molecular imaging of the gastrin-releasing peptide receptor (GRPR) could improve patient
management in prostate cancer. This study aimed to produce gallium-66 (T½= 9.5 h) …
management in prostate cancer. This study aimed to produce gallium-66 (T½= 9.5 h) …
Production, purification, and applications of a potential theranostic pair: cobalt-55 and cobalt-58m
The emerging success of [68Ga/177Lu] Ga/Lu-DOTATATE as a theranostic pair has spurred
interest in other isotopes as potential theranostic combinations. Here, we review cobalt-55 …
interest in other isotopes as potential theranostic combinations. Here, we review cobalt-55 …
New frontiers in molecular imaging using peptide-based radiopharmaceuticals for prostate cancer
X Li, H Cai, X Wu, L Li, H Wu, R Tian - Frontiers in Chemistry, 2020 - frontiersin.org
The high incidence of prostate cancer (PCa) increases the need for progress in its
diagnosis, staging, and precise treatment. The overexpression of tumor-specific receptors for …
diagnosis, staging, and precise treatment. The overexpression of tumor-specific receptors for …
Gastrin-releasing peptide receptor as theranostic target in estrogen-receptor positive breast cancer: A preclinical study of the theranostic pair [55Co] Co-and [177Lu] …
Background Patients with advanced metastatic estrogen receptor-positive breast cancer
often develop resistance to standard treatments, leading to uncontrolled progression. Thus …
often develop resistance to standard treatments, leading to uncontrolled progression. Thus …
A Systematic Investigation into the Influence of Net Charge on the Biological Distribution of Radiometalated Peptides Using [68Ga]Ga-DOTA-TATE Derivatives
Recently, several radiometalated peptides have been approved for clinical imaging and/or
therapy (theranostics) of several types of cancer; nonetheless, the primary challenge that …
therapy (theranostics) of several types of cancer; nonetheless, the primary challenge that …
Development of an Immuno-SPECT/Fluorescent Bimodal Tracer Targeting Human or Murine PD-L1 on Preclinical Models
M Privat, A Massot, F Hermetet… - Journal of Medicinal …, 2024 - ACS Publications
Detection of biomarkers to diagnose, treat, and predict the efficacy of cancer therapies is a
major clinical challenge. Currently, biomarkers such as PD-L1 are commonly detected from …
major clinical challenge. Currently, biomarkers such as PD-L1 are commonly detected from …
Positron Emission Tomography Imaging of Neurotensin Receptor-Positive Tumors with 68Ga-Labeled Antagonists: The Chelate Makes the Difference Again
E Renard, M Moreau, PS Bellaye… - Journal of Medicinal …, 2021 - ACS Publications
Neurotensin receptor 1 (NTS1) is involved in the development and progression of numerous
cancers, which makes it an interesting target for the development of diagnostic and …
cancers, which makes it an interesting target for the development of diagnostic and …