Fisetin is found in many fruits and plants such as grapes and onions, and exerts anti-
inflammatory, anti-proliferative, and anticancer activity. However, whether fisetin regulates …

Glycogen synthase kinase-3 (GSK-3) activity regulates multiple signal transduction
pathways and is also a key component of the network responsible for maintaining stem cell …

Generation of induced pluripotent stem (iPS) cells and cancer biogenesis share similar
metabolic switches. Most studies have focused on how the establishment of a cancer-like …

The toxicity of hexavalent chromium [Cr (VI)] in drinking water has been studied extensively,
and available in vivo and in vitro studies provide a robust dataset for application of …

Exposure to hexavalent chromium [Cr (VI)] in drinking water was previously reported to
increase oral tumor incidence in F344 rats. To investigate the mode of action for these …

Learning aptitude has never been a focus of visuospatial performance studies, particularly
on memory consolidation and reconsolidation. The aim of this study was to determine the …

This work aims to evaluate the impact of 2-morpholino-8-phenyl-4H-chromen-4-one
(LY294002) combined 5-fluorouracil (5-FU) for the activity of CD90+ liver cancer cells …

Glycogen synthase kinase-3 (Gsk-3) is a key regulator of multiple signal transduction
pathways. Recently we described a novel role for Gsk-3 in the regulation of DNA methylation …

Embryonic stem cells (ESCs) hold immense promise in regenerative medicine, yet the
precise regulatory mechanisms governing their pluripotency remain elusive. Recognized …

Fisetin is a plant secondary metabolite which is ubiquitously expressed in some of the fruits
and vegetables such as apple, strawberry, persimmon, onion, lotus root and cucumber. It is …