Emerging connections between cerebellar development, behaviour and complex brain disorders
A Sathyanesan, J Zhou, J Scafidi, DH Heck… - Nature Reviews …, 2019 - nature.com
The human cerebellum has a protracted developmental timeline compared with the
neocortex, expanding the window of vulnerability to neurological disorders. As the …
neocortex, expanding the window of vulnerability to neurological disorders. As the …
Consensus paper: experimental neurostimulation of the cerebellum
LN Miterko, KB Baker, J Beckinghausen, LV Bradnam… - The Cerebellum, 2019 - Springer
The cerebellum is best known for its role in controlling motor behaviors. However, recent
work supports the view that it also influences non-motor behaviors. The contribution of the …
work supports the view that it also influences non-motor behaviors. The contribution of the …
Cerebellar deep brain stimulation for chronic post-stroke motor rehabilitation: a phase I trial
Upper-extremity impairment after stroke remains a major therapeutic challenge and a target
of neuromodulation treatment efforts. In this open-label, non-randomized phase I trial, we …
of neuromodulation treatment efforts. In this open-label, non-randomized phase I trial, we …
[图书][B] Broken movement: the neurobiology of motor recovery after stroke
JW Krakauer, ST Carmichael - 2022 - books.google.com
An account of the neurobiology of motor recovery in the arm and hand after stroke by two
experts in the field. Stroke is a leading cause of disability in adults and recovery is often …
experts in the field. Stroke is a leading cause of disability in adults and recovery is often …
Cerebellum lecture: the cerebellar nuclei—core of the cerebellum
JM Kebschull, F Casoni, GG Consalez, D Goldowitz… - The Cerebellum, 2024 - Springer
The cerebellum is a key player in many brain functions and a major topic of neuroscience
research. However, the cerebellar nuclei (CN), the main output structures of the cerebellum …
research. However, the cerebellar nuclei (CN), the main output structures of the cerebellum …
Neuromodulation of the cerebellum rescues movement in a mouse model of ataxia
LN Miterko, T Lin, J Zhou, ME van der Heijden… - Nature …, 2021 - nature.com
Deep brain stimulation (DBS) relieves motor dysfunction in Parkinson's disease, and other
movement disorders. Here, we demonstrate the potential benefits of DBS in a model of …
movement disorders. Here, we demonstrate the potential benefits of DBS in a model of …
Subthalamic nucleus deep brain stimulation: basic concepts and novel perspectives
Over the last decades, extensive basic and clinical knowledge has been acquired on the
use of subthalamic nucleus (STN) deep brain stimulation (DBS) for Parkinson's disease …
use of subthalamic nucleus (STN) deep brain stimulation (DBS) for Parkinson's disease …
Purkinje cell misfiring generates high-amplitude action tremors that are corrected by cerebellar deep brain stimulation
AM Brown, JJ White, ME van der Heijden, J Zhou, T Lin… - Elife, 2020 - elifesciences.org
Tremor is currently ranked as the most common movement disorder. The brain regions and
neural signals that initiate the debilitating shakiness of different body parts remain unclear …
neural signals that initiate the debilitating shakiness of different body parts remain unclear …
Low-frequency stimulation enhances ensemble co-firing and dexterity after stroke
P Khanna, D Totten, L Novik, J Roberts, RJ Morecraft… - Cell, 2021 - cell.com
Electrical stimulation is a promising tool for modulating brain networks. However, it is
unclear how stimulation interacts with neural patterns underlying behavior. Specifically, how …
unclear how stimulation interacts with neural patterns underlying behavior. Specifically, how …
Functional brain network features specify DBS outcome for patients with treatment resistant depression
Deep brain stimulation (DBS) has shown therapeutic benefits for treatment resistant
depression (TRD). Stimulation of the subcallosal cingulate gyrus (SCG) aims to alter …
depression (TRD). Stimulation of the subcallosal cingulate gyrus (SCG) aims to alter …