Chronic obstructive pulmonary disease and COVID-19: interrelationships

D Singh, AG Mathioudakis… - Current opinion in …, 2022 - journals.lww.com
Chronic obstructive pulmonary disease and COVID-19: interrel... : Current Opinion in
Pulmonary Medicine Chronic obstructive pulmonary disease and COVID-19 …

Mechanism of rhinovirus immunity and asthma

Z Yang, H Mitländer, T Vuorinen, S Finotto - Frontiers in immunology, 2021 - frontiersin.org
The majority of asthma exacerbations in children are caused by Rhinovirus (RV), a positive
sense single stranded RNA virus of the Picornavirus family. The host has developed virus …

The establishment of COPD organoids to study host-pathogen interaction reveals enhanced viral fitness of SARS-CoV-2 in bronchi

LLY Chan, DE Anderson, HS Cheng, FX Ivan… - Nature …, 2022 - nature.com
Chronic obstructive pulmonary disease (COPD) is characterised by airflow limitation and
infective exacerbations, however, in-vitro model systems for the study of host-pathogen …

Increased SARS-CoV-2 infection, protease, and inflammatory responses in chronic obstructive pulmonary disease primary bronchial epithelial cells defined with …

MD Johansen, RM Mahbub, S Idrees… - American Journal of …, 2022 - atsjournals.org
Rationale: Patients with chronic obstructive pulmonary disease (COPD) develop more
severe coronavirus disease (COVID-19); however, it is unclear whether they are more …

Toll-like receptor-agonist-based therapies for respiratory viral diseases: thinking outside the cell

JLN Girkin, S Maltby, NW Bartlett - European Respiratory …, 2022 - Eur Respiratory Soc
Respiratory virus infections initiate in the upper respiratory tract (URT). Innate immunity is
critical for initial control of infection at this site, particularly in the absence of mucosal virus …

Viral infection and airway epithelial immunity in asthma

SR Kim - International journal of molecular sciences, 2022 - mdpi.com
Viral respiratory tract infections are associated with asthma development and exacerbation
in children and adults. In the course of immune responses to viruses, airway epithelial cells …

Advances in the relationship between respiratory viruses and asthma

SJ Romero-Tapia, CG Guzmán Priego… - Journal of Clinical …, 2023 - mdpi.com
Several studies have reported that viral infection is closely associated with the onset,
progression, and exacerbation of asthma. The purpose of this review is to summarize the …

IL-25 blockade augments antiviral immunity during respiratory virus infection

TC Williams, SL Loo, KS Nichol, AT Reid… - Communications …, 2022 - nature.com
IL-25 is implicated in the pathogenesis of viral asthma exacerbations. However, the effect of
IL-25 on antiviral immunity has yet to be elucidated. We observed abundant expression and …

In Vitro Modelling of Respiratory Virus Infections in Human Airway Epithelial Cells – A Systematic Review

LC Rijsbergen, LLA Van Dijk, MFM Engel… - Frontiers in …, 2021 - frontiersin.org
Respiratory tract infections (RTI) are a major cause of morbidity and mortality in humans. A
large number of RTIs is caused by viruses, often resulting in more severe disease in infants …

A toolbox for studying respiratory viral infections using air-liquid interface cultures of human airway epithelial cells

AN Michi, D Proud - American Journal of Physiology-Lung …, 2021 - journals.physiology.org
Submerged cultures of primary human airway epithelial cells or human airway epithelial cell
lines have been a mainstay of airway epithelial biology research for decades due to their …