Co-culture systems and technologies: taking synthetic biology to the next level

L Goers, P Freemont, KM Polizzi - Journal of The Royal …, 2014 - royalsocietypublishing.org
Co-culture techniques find myriad applications in biology for studying natural or synthetic
interactions between cell populations. Such techniques are of great importance in synthetic …

3D cell cultures as prospective models to study extracellular vesicles in cancer

G Bordanaba-Florit, I Madarieta, B Olalde… - Cancers, 2021 - mdpi.com
Simple Summary 3D cell cultures are a qualitative improvement in cancer research because
these models preserve cancer physiological characteristics better than traditional bi …

Artificial cell-cell communication as an emerging tool in synthetic biology applications

S Hennig, G Rödel, K Ostermann - Journal of biological engineering, 2015 - Springer
Cell-cell communication is a widespread phenomenon in nature, ranging from bacterial
quorum sensing and fungal pheromone communication to cellular crosstalk in multicellular …

Automated selection of synthetic biology parts for genetic regulatory networks

F Yaman, S Bhatia, A Adler, D Densmore… - ACS synthetic …, 2012 - ACS Publications
Raising the level of abstraction for synthetic biology design requires solving several
challenging problems, including mapping abstract designs to DNA sequences. In this paper …

Model reduction enables Turing instability analysis of large reaction–diffusion models

S Smith, N Dalchau - Journal of The Royal Society …, 2018 - royalsocietypublishing.org
Synthesizing a genetic network which generates stable Turing patterns is one of the great
challenges of synthetic biology, but a significant obstacle is the disconnect between the …

Turing patterning in stratified domains

AL Krause, V Klika, J Halatek, PK Grant… - Bulletin of Mathematical …, 2020 - Springer
Reaction–diffusion processes across layered media arise in several scientific domains such
as pattern-forming E. coli on agar substrates, epidermal–mesenchymal coupling in …

Synthetic biology in various cellular and molecular fields: applications, limitations, and perspective

M Safaei, GR Mobini, A Abiri, A Shojaeian - Molecular Biology Reports, 2020 - Springer
Synthetic biology breakthroughs have facilitated genetic circuit engineering to program cells
through novel biological functions, dynamic gene expressions, as well as logic controls …

Cell-encapsulating hydrogels for biosensing

P Chen, S Wang, F Inci, S Güven… - … Volume 3: Application …, 2016 - World Scientific
Cell-based biosensors (CBBs) are emerging as a sensing platform in which live cells are
utilized to sense external stimuli including physical, chemical, and biological changes. Till …

[PDF][PDF] 3D Cell Cultures as Prospective Models to Study Extracellular Vesicles in Cancer. Cancers 2021, 13, 307

G Bordanaba-Florit, I Madarieta, B Olalde… - 2021 - repository.journal4submission.com
The improvement of culturing techniques to model the environment and physiological
conditions surrounding tumors has also been applied to the study of extracellular vesicles …

Programming languages for circuit design

M Pedersen, B Yordanov - Computational Methods in Synthetic Biology, 2015 - Springer
This chapter provides an overview of a programming language for Genetic Engineering of
Cells (GEC). A GEC program specifies a genetic circuit at a high level of abstraction through …