Epithelial cells require apical–basal plasma membrane polarity to carry out crucial vectorial
transport functions and cytoplasmic polarity to generate different cell progenies for tissue …

More than 80 different adenovirus (AdV) types infect humans through the respiratory, ocular,
or gastrointestinal tracts. They cause acute clinical mani-festations or persist under humoral …

The endosomal system is expansive and complex, characterized by swift morphological
transitions, dynamic remodeling of membrane constituents, and intracellular positioning …

The trans-Golgi network (TGN) is an important cargo sorting station within the cell where
newly synthesized proteins are packaged into distinct transport carriers that are targeted to …

Polarized cells such as epithelial cells and neurons exhibit different plasma membrane
domains with distinct protein compositions. Recent studies have shown that sorting of …

AP-1 is a clathrin adaptor complex that sorts cargo between the trans-Golgi network and
endosomes. AP-1 recruitment to these compartments requires Arf1-GTP. The crystal …

Epithelial cells have an apical–basolateral axis of polarity, which is required for epithelial
functions including barrier formation, vectorial ion transport and sensory perception. Here …

Members of the interferon‐induced transmembrane (IFITM) protein family inhibit the entry of
a wide range of viruses. Viruses often exploit the endocytosis pathways to invade host cells …

Renal epithelial cells must maintain distinct protein compositions in their apical and
basolateral membranes in order to perform their transport functions. The creation of these …

The retinal pigment epithelium (RPE) comprises a monolayer of polarized pigmented
epithelial cells that is strategically interposed between the neural retina and the fenestrated …