Analyzing the mechanisms of iron oxide nanoparticles interactions with cells: A road from failure to success in clinical applications

A Frtús, B Smolková, M Uzhytchak, M Lunova… - Journal of Controlled …, 2020 - Elsevier
Iron oxide nanoparticles (IONPs) were the first generation of nanomaterials that reached real
clinic use. Particularly, several IONPs-based magnetic resonance imaging contrast agents …

[HTML][HTML] Nanoparticles as smart carriers for enhanced cancer immunotherapy

N Thakur, S Thakur, S Chatterjee, J Das… - Frontiers in Chemistry, 2020 - frontiersin.org
Cancer immunotherapy has emerged as a promising strategy for the treatment of many
forms of cancer by stimulating body's own immune system. This therapy not only eradicates …

A novel photothermally controlled multifunctional scaffold for clinical treatment of osteosarcoma and tissue regeneration

L Ma, X Feng, H Liang, K Wang, Y Song, L Tan… - Materials Today, 2020 - Elsevier
After an osteosarcoma excision, recurrence, large bone defects, and soft tissue injury are
significant challenges for clinicians. Conventional treatment by implanting bone replacement …

H2S‐Scavenged and Activated Iron Oxide‐Hydroxide Nanospindles for MRI‐Guided Photothermal Therapy and Ferroptosis in Colon Cancer

Y Li, W Chen, Y Qi, S Wang, L Li, W Li, T Xie, H Zhu… - Small, 2020 - Wiley Online Library
Overproduced hydrogen sulfide (H2S) is of vital importance for the progress of colon cancer
and promotes cancer cellular proliferation. Devising pharmacological nanomaterials for …

Cu2MoS4/Au Heterostructures with Enhanced Catalase‐Like Activity and Photoconversion Efficiency for Primary/Metastatic Tumors Eradication by Phototherapy …

M Chang, Z Hou, M Wang, M Wang, P Dang, J Liu… - Small, 2020 - Wiley Online Library
Photoimmunotherapy can not only effectively ablate the primary tumor but also trigger strong
antitumor immune responses against metastatic tumors by inducing immunogenic cell …

A review of biomimetic scaffolds for bone regeneration: toward a cell‐free strategy

S Jiang, M Wang, J He - Bioengineering & Translational …, 2021 - Wiley Online Library
In clinical terms, bone grafting currently involves the application of autogenous, allogeneic,
or xenogeneic bone grafts, as well as natural or artificially synthesized materials, such as …

Plasmonically modulated gold nanostructures for photothermal ablation of bacteria

G Guan, KY Win, X Yao, W Yang… - Advanced Healthcare …, 2021 - Wiley Online Library
With the wide utilization of antibiotics, antibiotic‐resistant bacteria have been often
developed more frequently to cause potential global catastrophic consequences. Emerging …

Multistage-responsive clustered nanosystem to improve tumor accumulation and penetration for photothermal/enhanced radiation synergistic therapy

S Hua, J He, F Zhang, J Yu, W Zhang, L Gao, Y Li… - Biomaterials, 2021 - Elsevier
Developing new strategies to overcome biological barriers and achieve efficient delivery of
therapeutic nanoparticles (NPs) is the key to achieve positive therapeutic outcomes in …

Rhombohedron and plate-like hematite (α-Fe2O3) nanoparticles: synthesis, structure, morphology, magnetic properties and potential biomedical applications for MRI

M Tadic, L Kopanja, M Panjan, J Lazovic… - Materials Research …, 2021 - Elsevier
Hematite nanorhombohedrons and nanoplates have been prepared through a hydrothermal
synthesis process. The nanoplates possess width of 100 nm and thickness of 30 nm …

Photothermal nanozyme-ignited Fenton reaction-independent ferroptosis for breast cancer therapy

L Xing, XY Liu, TJ Zhou, X Wan, Y Wang… - Journal of Controlled …, 2021 - Elsevier
Ferroptosis is a type of programmed cell death caused by the iron-dependent lipid
hydroperoxide pathway and has attracted significant interest. However, Fenton reaction …