Cell monolayers sense curvature by exploiting active mechanics and nuclear mechanoadaptation
The early development of many organisms involves the folding of cell monolayers, but this
behaviour is difficult to reproduce in vitro; therefore, both mechanistic causes and effects of …
behaviour is difficult to reproduce in vitro; therefore, both mechanistic causes and effects of …
Tumorigenic mesenchymal clusters are less sensitive to moderate osmotic stresses due to low amounts of junctional E-cadherin
The migration of tumorigenic cells is a critical step for metastatic breast cancer progression.
Although the role of the extracellular matrix in breast cancer cell migration has been …
Although the role of the extracellular matrix in breast cancer cell migration has been …
Large-scale curvature sensing by epithelial monolayers depends on active cell mechanics and nuclear mechanoadaptation
While many tissues fold in vivo in a highly reproducible and robust way, epithelial folds
remain difficult to reproduce in vitro, so that the effects and underlying mechanisms of local …
remain difficult to reproduce in vitro, so that the effects and underlying mechanisms of local …
Collective cell migration during human mammary gland organoid morphogenesis
FP Hutterer, B Buchmann, LK Engelbrecht… - Biophysics …, 2022 - pubs.aip.org
Organ morphogenesis is driven by cellular migration patterns, which become accessible for
observation in organoid cultures. We demonstrate here that mammary gland organoids …
observation in organoid cultures. We demonstrate here that mammary gland organoids …
Tumorigenic epithelial clusters are less sensitive to moderate osmotic stresses due to low amounts of junctional E-cadherin
The migration of tumorigenic epithelial cells is a critical step for metastatic breast cancer
progression. Although the role of the extracellular matrix in breast cancer cell migration has …
progression. Although the role of the extracellular matrix in breast cancer cell migration has …