Heterocycles are the key structures in organic chemistry owing to their immense applications
in the biological, chemical, and pharmaceutical fields. Heterocyclic compounds perform …

N-heterocycles are crucial due to their biological, chemical, and practical significance. They
are heavily investigated in biological processes involving anticancer, anti-inflammatory …

TB being one of the deadliest diseases and second most common infectious cause of
deaths, poses the severe threat to global health. The extended duration of therapy owing to …

Aryl amidoximes are active binucleophilic compounds used as a powerful and versatile
reagent in synthesizing diverse heterocyclic compounds with pharmacological interest …

The mounting evidence of bacterial resistance against commonly prescribed antibiotics
warrants the development of new antibacterial drugs on an urgent basis. Linezolid, an …

One of the biggest health challenges of today's world is the emergence of antimicrobial
resistance (AMR), which renders conventional therapeutics insufficient and urgently …

Tuberculosis (TB) remains a widespread infectious disease and one of the top 10 causes of
death worldwide. Nevertheless, despite significant advances in the development of new …

Oxazolidinones are one of the well-known classes of O-heterocycles which has yielded
various potent antibiotics. Several oxazolidinone-based antibiotics are either FDA-approved …

Aim: To design, synthesize and evaluate oxindole derivatives for antitubercular activity.
Methodology: We synthesized the derivatives, confirmed their structures by 1H/13C NMR …

Antimicrobial resistance caused by the emergence of antibiotic‐resistant microbes, termed
as “superbugs,” poses a grave healthcare concern in the contemporary era. Though this …