Autophagy is a conserved process in which the cytosolic materials are degraded and
eventually recycled for cellular metabolism to maintain homeostasis. The dichotomous role …

With the rapid development of nanotechnology, inorganic nanomaterials (NMs) have been
widely applied in modern society. As human exposure to inorganic NMs is inevitable …

Endothelial cells integrally form a crucial interface that maintains homeostasis of the
cardiovascular system. As a vulnerable target of PM2. 5, the underlying mechanisms of …

Owing to the increasing application of engineered nanoparticles (NPs), besides the
workplace, human beings are also exposed to NPs from nanoproducts through the skin …

Nanotechnology has gained significant development over the past decades, which led to the
revolution in the fields of information, medicine, industry, food security and aerospace …

Targeting autophagy may serve as a promising strategy for cancer therapy. Ganoderma
lucidum polysaccharide (GLP) has been shown to exert promising anti-cancer effects …

Tumor metastasis and recurrence is one of the biggest problems in curing cancers. Due to
the difficulty in complete removal of the primary tumor in traditional surgeries and the poor …

The ubiquity of microplastics increases the exposure risks and health threats to humans. In
this study, rat basophilic leukemia (RBL-2H3) cells were exposed to polystyrene particles …

Background Widespread biomedical applications of nanomaterials (NMs) bring about
increased human exposure risk due to their unique physicochemical properties. Autophagy …

Background Pancreatic cancer has been characterized by poor prognosis, early metastasis
and dissatisfactory treatment outcome. The high basal level of autophagy in tumor cells …