The forgotten people: Hepatitis B virus (HBV) infection as a priority for the inclusion health agenda

E Martyn, S Eisen, N Longley, P Harris, J Surey… - Elife, 2023 - elifesciences.org
Hepatitis B virus (HBV) infection represents a significant global health threat, accounting for
300 million chronic infections and up to 1 million deaths each year. HBV disproportionately …

[HTML][HTML] Development of hepatocellular carcinoma in treated and untreated patients with chronic hepatitis B virus infection

CL Lin, JH Kao - Clinical and Molecular Hepatology, 2023 - ncbi.nlm.nih.gov
Hepatitis B virus (HBV) is responsible for more than 50% of hepatocellular carcinoma (HCC)
in HBV hyperendemic areas, such as the Asia-Pacific region. Several hepatitis B viral factors …

HBx-induced HSPA8 stimulates HBV replication and suppresses ferroptosis to support liver cancer progression

Y Wang, M Zhao, L Zhao, Y Geng, G Li, L Chen, J Yu… - Cancer Research, 2023 - AACR
Hepatitis B virus (HBV) infection is a major driver of hepatocarcinogenesis. Ferroptosis is a
type of iron-mediated cell death that can suppress liver transformation. Previous studies …

Guidelines for the prevention and treatment of chronic hepatitis B (version 2022)

H You, FS Wang, T Li, X Xu, Y Sun, Y Nan… - Infectious Diseases & …, 2023 - mednexus.org
To facilitate the achieving of the goal of" eliminating viral hepatitis as a major public health
threat by 2030" set by the World Health Organization, the Chinese Society of Hepatology …

[HTML][HTML] Impact of diabetes, obesity, and dyslipidemia on the risk of hepatocellular carcinoma in patients with chronic liver diseases

HS Shin, BG Jun, SW Yi - Clinical and Molecular Hepatology, 2022 - ncbi.nlm.nih.gov
Despite the increasing prevalence of metabolic disorders, the potential effects of metabolic
factors on hepatocellular carcinoma (HCC) development in individuals with chronic liver …

The emerging role of metformin in the treatment of hepatocellular carcinoma: is there any value in repurposing metformin for HCC immunotherapy?

SP Papadakos, D Ferraro, G Carbone, AE Frampton… - Cancers, 2023 - mdpi.com
Simple Summary The study investigates the potential use of metformin, a medication
commonly prescribed for type 2 diabetes, in the treatment of hepatocellular carcinoma …

Enhancing HCC Treatment: innovatively combining HDAC2 inhibitor with PD-1/PD-L1 inhibition

R Han, C Ling, Y Wang, L Lu - Cancer Cell International, 2023 - Springer
Hepatocellular carcinoma (HCC) is a malignancy with high morbidity and mortality but lacks
effective treatments thus far. Although the emergence of immune checkpoint inhibitors in …

Overview of hepatocellular carcinoma: from molecular aspects to future therapeutic options

S Panneerselvam, C Wilson, P Kumar… - Cell Adhesion & …, 2023 - Taylor & Francis
Hepatocellular carcinoma (HCC) is the seventh most highly prevalent malignant tumor
globally and the second most common cause of mortality. HCC develops with complex …

The role of NUPR1 in response to stress and cancer development

S Liu, M Costa - Toxicology and Applied Pharmacology, 2022 - Elsevier
Stress contributes to the development of many human diseases, including cancer. Based on
the source of stress, it can be divided into external stress, such as environmental …

Diabetic MAFLD is associated with increased risk of hepatocellular carcinoma and mortality in chronic viral hepatitis patients

MN Kim, K Han, J Yoo, SG Hwang… - … Journal of Cancer, 2023 - Wiley Online Library
Metabolic dysfunction‐associated fatty liver disease (MAFLD) can coexist with chronic viral
hepatitis. MAFLD is a heterogeneous disease because the diagnostic criteria include …