Articular cartilage injury is a frequent worldwide disease, while effective treatment is urgently
needed. Due to lack of blood vessels and nerves, the ability of cartilage to self-repair is …

Three-dimensional (3D) bioprinting is an additive manufacturing process that utilizes various
biomaterials that either contain or interact with living cells and biological systems with the …

Three-dimensional (3D) bioprinting of hydrogel-based constructs at adequate consistency
and reproducibility can be obtained through a compromise between the hydrogel's inherent …

Achieving and maintaining safe and reliable lineage specific differentiation of stem cells is
important for clinical translation of tissue engineering strategies. In an effort to circumvent the …

Mesenchymal stem cell derived extracellular matrix (MSC-ECM) is a natural biomaterial with
robust bioactivity and good biocompatibility, and has been studied as a scaffold for tissue …

Ideal tissue-engineering cartilage scaffolds should possess the same nanofibrous structure
as the microstructure of native cartilage as well as the same biological function provided by …

Bioactive scaffolds from synthetical polymers or decellularized cartilage matrices have been
widely used in osteochondral regeneration. However, the risks of potential immunological …

Over the past decades, numerous tissue-engineered constructs have been investigated for
the osteochondral repair. However, it still remains a challenge to regenerate the …

Cartilaginous extracellular matrix (ECM) materials derived from decellularized native
articular cartilage are widely used in cartilage regeneration. However, it is difficult for …

A 3-D scaffold that simulates the microenvironment in vivo for regenerating cartilage is ideal.
In this study, we combined silk fibroin and decellularized cartilage extracellular matrix by …