[HTML][HTML] Natural medicine in neuroprotection for ischemic stroke: Challenges and prospective
T Tao, M Liu, M Chen, Y Luo, C Wang, T Xu… - Pharmacology & …, 2020 - Elsevier
There is a growing interest in using natural medicines to treat stroke as the leading cause of
disability worldwide. Especially plant-derived natural medicines have multiple beneficial …
disability worldwide. Especially plant-derived natural medicines have multiple beneficial …
Multifunctional compounds: Smart molecules for multifactorial diseases
Y Bansal, O Silakari - European Journal of Medicinal Chemistry, 2014 - Elsevier
Multifunctional compounds (MFCs) are designed broadly as hybrid or conjugated drugs or
as chimeric drugs from two or more pharmacophores/drugs having specific pharmacological …
as chimeric drugs from two or more pharmacophores/drugs having specific pharmacological …
50/50 oil/water emulsion stabilized by pea protein isolate microgel particles/xanthan gum complexes and co-emulsifiers
Abstract Properties of 50/50 oil/water emulsion stabilized by pea protein isolate microgel
particles (PPIMP)/xanthan gum (XG) and co-emulsifiers were evaluated. Three surfactants …
particles (PPIMP)/xanthan gum (XG) and co-emulsifiers were evaluated. Three surfactants …
[HTML][HTML] Mitochondrial MPTP: a novel target of ethnomedicine for stroke treatment by apoptosis inhibition
Y Li, J Sun, R Wu, J Bai, Y Hou, Y Zeng… - Frontiers in …, 2020 - frontiersin.org
Mammalian mitochondrial permeability transition pore (MPTP), across the inner and outer
membranes of mitochondria, is a nonspecific channel for signal transduction or material …
membranes of mitochondria, is a nonspecific channel for signal transduction or material …
Age-associated neurodegeneration and oxidative damage to lipids, proteins and DNA
Lipids, proteins and DNA in the central nervous system have a high sensitivity to oxidative
stress. Reactive oxygen species (ROS)-induced damage increases with aging, especially in …
stress. Reactive oxygen species (ROS)-induced damage increases with aging, especially in …
Multiomics analyses of two Leonurus species illuminate leonurine biosynthesis and its evolution
P Li, MX Yan, P Liu, DJ Yang, ZK He, Y Gao, Y Jiang… - Molecular Plant, 2024 - cell.com
The Lamiaceae family is renowned for its terpenoid-based medicinal components, but
Leonurus, which has traditional medicinal uses, stands out for its alkaloid-rich composition …
Leonurus, which has traditional medicinal uses, stands out for its alkaloid-rich composition …
[HTML][HTML] Leonurus japonicus (Chinese motherwort), an excellent traditional medicine for obstetrical and gynecological diseases: A comprehensive overview
LL Miao, QM Zhou, C Peng, ZH Liu, L Xiong - Biomedicine & …, 2019 - Elsevier
Leonurus japonicus Houtt. is a traditional medicinal herb with significant effects; dating back
more than 1800 years, it is widely used in Asia. In traditional Chinese medicine, it is …
more than 1800 years, it is widely used in Asia. In traditional Chinese medicine, it is …
[HTML][HTML] Energy-stress-mediated AMPK activation promotes GPX4-dependent ferroptosis through the JAK2/STAT3/P53 axis in renal cancer
Y Li, Y Zhang, Q Qiu, L Wang, H Mao, J Hu… - … medicine and cellular …, 2022 - hindawi.com
Energy stress is an unfavorable condition that tumor cells are often exposed to. Ferroptosis
is considered an emerging target for tumor therapy. However, the role of ferroptosis in …
is considered an emerging target for tumor therapy. However, the role of ferroptosis in …
Sustainable production of active pharmaceutical ingredients from lignin-based benzoic acid derivatives via “demand orientation”
Research related to lignin valorization into fine chemicals is an extremely demanding task
due to the wide distribution and low economic value of depolymerization products. Benzoic …
due to the wide distribution and low economic value of depolymerization products. Benzoic …
Success stories of natural product-based hybrid molecules for multi-factorial diseases
Complex diseases comprises of highly complicated etiology resulting in limited applicability
of conventional targeted therapies. Consequently, conventional medicinal compounds suffer …
of conventional targeted therapies. Consequently, conventional medicinal compounds suffer …