Cancer immunotherapy is a rapidly evolving concept that has been given the tag" fifth pillar"
of cancer therapy while radiation therapy, chemotherapy, surgery and targeted therapy …

Background The pan-immune-inflammation value (PIV) has been reported as a novel
prognostic biomarker in multiple malignancies. The aim of this study is to investigate the …

The oncogenic effects of long non-coding RNA (lncRNA) Nicotinamide Nucleotide
Transhydrogenase-antisense RNA1 (NNT-AS1) role in colorectal cancer (CRC) hasn't been …

Background Breast cancer is a highly heterogeneous disease, this poses challenges for
classification and management. Long non-coding RNAs play acrucial role in the breast …

Colorectal cancer (CRC) is the third highest incidence and the second highest mortality
malignant tumor in the world. The etiology and pathogenesis of CRC are complex. Due to …

Gastrointestinal (GI) cancer includes many cancer types, such as esophageal, liver, gastric,
pancreatic, and colorectal cancer. As the cornerstone of personalized medicine for GI …

Background Transgenic C57BL/6-APC (Min/+) spontaneous cancer mouse model and the
Azoxymethane (AOM)/Dextran Sulfate Sodium (DSS) chemically induced orthotopic …

Background Lung cancer is the most common cancer and cause of cancer‐related mortality
worldwide, increasing evidence indicated that there was a significant correlation between …

Abstract Metadherin (AEG-1/MTDH/LYRIC) is a 582-amino acid transmembrane protein,
encoded by a gene located at chromosome 8q22, and distributed throughout the cytoplasm …

Extracellular vesicles (EVs) are produced by all cells in the body. These biological
nanoparticles facilitate cellular communication through the transport of diverse cargoes …