Abstract The Canadian Consensus Working Group has updated its evaluation of the
literature pertaining to statin intolerance and adverse effects. This overview introduces a …

Aims As the potential impact of statins on cognitive decline and dementia is still debated, we
conducted a meta-analysis of observational studies to examine the effect of statin use on the …

Antidepressants are the most commonly and widely used medication for its effectiveness in
the treatment of anxiety and depression. A few epidemiological studies have documented …

Background: Epidemiological evidence has associated Alzheimer's disease (AD) with
vascular risk factors (VRFs), but whether treatment of VRFs reduces the incidence of …

The protective effect of statin on Alzheimer disease (AD) is still controversial, probably due to
the debate about when to start the use of statin and the lack of any large-scale randomized …

Alzheimer's disease (AD) is the leading cause of dementia affecting almost 50 million
people worldwide. The ε4 allele of Apolipoprotein E (APOE) is the strongest known genetic …

Background: Evidence summaries for efficacy and safety of frequently employed treatments
of Alzheimer's disease (AD) are sparse. Objective: We aimed to perform an updated …

Abstract Introduction Benzodiazepines (BZDs) are commonly prescribed for anxiety and
agitations, which are early symptoms of Alzheimer's disease and related dementias (ADRD) …

Objective Alzheimer's disease (AD) is a common type of dementia, which has caused heavy
global economic and health burden, and the using of statins to treat AD has caused widely …

Abstract The US Food and Drug Administration issued a black box warning in 2012
regarding the association of statin use with cognitive impairment. This may deter patients …