Intermittent hypoxia (IH) has been the subject of considerable research in recent years, and
triggers a bewildering array of both detrimental and beneficial effects in multiple …

Erythropoietin (EPO) is a glycoprotein cytokine known for its pleiotropic effects on various
types of cells and tissues. EPO and its receptor EPOR trigger signaling cascades …

Ventilatory responses to hypoxia vary widely depending on the pattern and length of hypoxic
exposure. Acute, prolonged, or intermittent hypoxic episodes can increase or decrease …

Intermittent hypoxia (IH) is most often thought of for its role in morbidity associated with sleep-
disordered breathing, including central nervous system pathology. However, recent …

In light of the present therapeutic situation in COVID-19, any measure to improve course and
outcome of seriously affected individuals is of utmost importance. We recap here evidence …

Erythropoietin (EPO) regulation of red blood cell production and its induction at reduced
oxygen tension provides for the important erythropoietic response to ischemic stress. The …

As in other neural systems, plasticity is a hallmark of the neural system controlling breathing.
One spinal mechanism of respiratory plasticity is phrenic long‐term facilitation (pLTF) …

Rationale: Amyotrophic lateral sclerosis (ALS) is a devastating motor neuron disease
causing paralysis and death from respiratory failure. Strategies to preserve and/or restore …

Acute intermittent hypoxia (AIH) elicits a form of spinal respiratory plasticity known as
phrenic long-term facilitation (pLTF). pLTF requires spinal serotonin receptor-2 activation …

Inflammation is characteristic of most clinical disorders that challenge the neural control of
breathing. Since inflammation modulates neuroplasticity, we studied the impact of …