The emergence of carbapenem-resistant Gram-negative pathogens poses a serious threat
to public health worldwide. In particular, the increasing prevalence of carbapenem-resistant …

The spread of Enterobacteriaceae, primarily Klebsiella pneumoniae, producing KPC, VIM,
IMP, and NDM carbapenemases, is causing an unprecedented public health crisis …

Carbapenem-hydrolysing β-lactamases are the most powerful β-lactamases, being able to
hydrolyse almost all β-lactams. They are mostly of the KPC, VIM, IMP, NDM and OXA-48 …

The modified Hodge test has an excellent sensitivity for detecting enterobacterial isolates
producing Ambler class A (KPC) and class D (OXA-48) carbapenemases. Its sensitivity is …

Matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry is
used for the determination of molecular weights of different chemical compounds. We …

Carbapenemase-producing bacteria have now spread all over the world. Infections caused
by those bacteria are difficult to treat. Therefore, there is an urgent need for accurate and fast …

Multidrug-resistant Enterobacterales (MDRE) are an emerging threat to global health,
leading to rising health care costs, morbidity and mortality. Multidrug-resistance is commonly …

ABSTRACT A biochemical test (Carba NP test II) was developed to identify carbapenemase
production in Enterobacteriaceae and Pseudomonas spp. and to discriminate between the …

The emergence and global spread of carbapenemase-producing Enterobacteriaceae is of
great concern to health services worldwide. These bacteria are often resistant to all beta …

Carbapenem-resistant Enterobacteriaceae (CRE) are emerging as a public health problem
in various settings. In Italy, a rapid and remarkable increase of carbapenem-non-susceptible …