[HTML][HTML] Efficacy and safety of tranexamic acid in acute traumatic brain injury: a systematic review and meta-analysis of randomized-controlled trials

KA Lawati, S Sharif, SA Maqbali, HA Rimawi… - Intensive care …, 2021 - Springer
Purpose With the publication of a large randomized-controlled trial (RCT) suggesting that
tranexamic acid (TXA) may improve head-injury-related deaths, we aimed to determine the …

[HTML][HTML] Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an …

I Roberts, H Shakur-Still, A Afolabi, A Akere, M Arribas… - The Lancet, 2020 - thelancet.com
Background Tranexamic acid reduces surgical bleeding and reduces death due to bleeding
in patients with trauma. Meta-analyses of small trials show that tranexamic acid might …

Tranexamic acid for gastrointestinal bleeding: a systematic review with meta-analysis of randomized clinical trials

PL Lee, KS Yang, HW Tsai, SK Hou, YN Kang… - The American Journal of …, 2021 - Elsevier
Background Acute gastrointestinal bleeding is a common life-threatening emergent
condition. Immediate tranexamic acid is useful for reducing hemorrhage following operation …

Bleeding from gynecologic malignancies

ML Hutchcraft, RW Miller - Obstetrics and Gynecology Clinics, 2022 - obgyn.theclinics.com
Vaginal bleeding is a common presenting symptom of several gynecologic malignancies.
Postmenopausal vaginal bleeding occurs in 90% of women diagnosed with endometrial …

A high-dose 24-hour tranexamic acid infusion for the treatment of significant gastrointestinal bleeding: HALT-IT RCT

I Roberts, H Shakur-Still, A Afolabi, A Akere… - Health Technology …, 2021 - ora.ox.ac.uk
Background Tranexamic acid reduces blood loss in surgery and the risk of death in trauma
patients. Meta-analyses of small trials suggest that tranexamic acid decreases the number of …

Catalysing global surgery: a meta-research study on factors affecting surgical research collaborations with Africa

TO Kirengo, H Dossajee, EM Onyango… - Systematic …, 2024 - Springer
Abstract Introduction In December 2019, the COVID-19 pandemic highlighted the urgent
need for rapid collaboration, research, and interventions. International research …

Comparison of the effectiveness and safety of intravenous and topical regimens of tranexamic acid in complex tibial plateau fracture: a retrospective study

Z Wang, Y Lu, Q Wang, L Song, T Ma, C Ren… - BMC musculoskeletal …, 2020 - Springer
Background Previous studies have demonstrated the effectiveness and safety of tranexamic
acid (TXA) in orthopedic surgery. However, no study has investigated TXA in complex tibial …

[HTML][HTML] Efficacy and safety of tranexamic acid in the treatment of gastric cancer complicated with upper gastrointestinal bleeding

Z Bai, L Wang, B Yu, D Xing, J Su… - American Journal of …, 2024 - ncbi.nlm.nih.gov
Objective: To investigate the efficacy and safety of tranexamic acid (TXA) in preventing
upper gastrointestinal (GI) bleeding in patients with gastric cancer. Methods: The clinical …

[HTML][HTML] Incidence and mortality related to gastrointestinal bleeding, and the effect of tranexamic acid on gastrointestinal bleeding

Y Scherdin, I Halldestam, S Redeen - Gastroenterology Research, 2021 - ncbi.nlm.nih.gov
Background Gastrointestinal bleeding is a common and potentially life-threatening
condition. The incidence of gastrointestinal bleeding has not decreased despite new …

Managing a patient presenting to the emergency department with upper gastrointestinal bleeding

SM Haigh - Emergency Nurse, 2022 - journals.rcni.com
Upper gastrointestinal (GI) bleeding is a common presentation in emergency departments
(EDs). This medical emergency has a mortality rate of up to 14%, particularly in men and …