Type II transmembrane serine proteases as modulators in adipose tissue phenotype and function
Q Wu, S Li, X Zhang, N Dong - Biomedicines, 2023 - mdpi.com
Adipose tissue is a crucial organ in energy metabolism and thermoregulation. Adipose
tissue phenotype is controlled by various signaling mechanisms under pathophysiological …
tissue phenotype is controlled by various signaling mechanisms under pathophysiological …
Transmembrane serine protease TMPRSS2 implicated in SARS-CoV-2 infection is autoactivated intracellularly and requires N-glycosylation for regulation
Y Zhang, S Sun, C Du, K Hu, C Zhang, M Liu… - Journal of Biological …, 2022 - ASBMB
Transmembrane protease serine 2 (TMPRSS2) is a membrane-bound protease expressed
in many human epithelial tissues, including the airway and lung. TMPRSS2-mediated …
in many human epithelial tissues, including the airway and lung. TMPRSS2-mediated …
[HTML][HTML] Development of ketobenzothiazole-based peptidomimetic TMPRSS13 inhibitors with low nanomolar potency
A Joushomme, A Désilets, W Champagne… - BioRxiv, 2024 - pmc.ncbi.nlm.nih.gov
TMPRSS13, a member of the Type II Transmembrane Serine Proteases (TTSP) family, is
involved in cancer progression and in cell entry of respiratory viruses. To date, no inhibitors …
involved in cancer progression and in cell entry of respiratory viruses. To date, no inhibitors …
Spatial position is a key determinant of N‐glycan functionality of the scavenger receptor cysteine‐rich domain of human hepsin
S Sun, K Hu, L Wang, M Liu, Y Zhang… - The FEBS …, 2023 - Wiley Online Library
The scavenger receptor cysteine‐rich (SRCR) domain is a key constituent in diverse
proteins. N‐glycosylation is important in protein expression and function. In the SRCR …
proteins. N‐glycosylation is important in protein expression and function. In the SRCR …