[HTML][HTML] Aminoacyl-tRNA synthetases of the multi-tRNA synthetase complex and their role in tumorigenesis

K Khan, V Gogonea, PL Fox - Translational Oncology, 2022 - Elsevier
In mammalian cells, 20 aminoacyl-tRNA synthetases (AARS) catalyze the ligation of amino
acids to their cognate tRNAs to generate aminoacylated-tRNAs. In higher eukaryotes, 9 of …

RNA-binding proteins signature is a favorable biomarker of prognosis, immunotherapy and chemotherapy response for cervical cancer

X Chen, X Dong, H Li, T Wu, H Liu, J Wu, W Ge… - Cancer Cell …, 2024 - Springer
Cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC) still present a
huge threaten to women's health, especially the local advanced patients. Hence, developing …

[HTML][HTML] Integration of meta-analysis and supervised machine learning for pattern recognition in breast cancer using epigenetic data

R Panahi, E Ebrahimie, A Niazi, A Afsharifar - Informatics in Medicine …, 2021 - Elsevier
Breast cancer is one of the most widespread diseases with high incidence and mortality rate
in females. The accurate biomarker discovery for the early detection of patients prone to …

[HTML][HTML] Pan-cancer Analysis Identifies AIMP2 as a Potential Biomarker for Breast Cancer

J Qiu, T Zhou, D Wang, W Hong, D Qian, X Meng… - Current …, 2023 - ncbi.nlm.nih.gov
Materials and Methods To assess AIMP2's role in tumor immunity, we conducted a pan-
cancer multi-database analysis using the Cancer Genome Atlas (TCGA), Genotype-Tissue …

The Study of SRSF1 Regulates Abnormal Alternative Splicing of BCL2L11 and the Role in Refractory Acute Ayeloid Leukemia

Q Wang, Y Duan, Z Zan, K Yang, J Wang, F Jia, Y Tan… - Chemotherapy, 2024 - karger.com
Introduction: Abnormalities in splicing factors, such as mutations or deregulated expression,
can lead to aberrant splicing of target genes, potentially contributing to the pathogenesis of …

CBX3 is a prognostic biomarker correlated with ATR activation and immune infiltration in head and neck squamous cell carcinoma

X Zhang, W Zhou, Y Zhang, Z Liu - International Journal of General …, 2022 - Taylor & Francis
Background Chromobox protein homolog (CBX) family members play important roles in the
progression and prognosis of many cancers. However, their functional role in head and neck …

[PDF][PDF] Informatics in Medicine Unlocked

Y Hayashi, S Nakano, S Fujisawa - Informatics in medicine …, 2015 - ci.cs.meiji.ac.jp
abstract Diabetes is a complex disease that is increasing in prevalence around the world.
Type 2 diabetes mellitus (T2DM) accounts for about 90–95% of all diagnosed adult cases of …

[PDF][PDF] Establishment of A Risk-Predicting Twenty-Two-Gene Signature Based on the Prognosis-Related RNA Binding Proteins of Breast Cancer

T Zhu, X Zhu, J Bu, Y Jiang, J Xue, N Niu, X Gu - 2021 - assets-eu.researchsquare.com
Background Breast cancer has been the leading cause of death among women worldwide.
RNA-binding proteins (RBPs) are promising novel biomarkers for patients with malignant …