Age-associated cerebral small vessel disease (CSVD) represents a clinically heterogenous
condition, arising from diverse microvascular mechanisms. These lead to chronic …

Immunofluorescence assays are extensively used for the detection of disease-associated
biomarkers within patient samples for direct diagnosis. Unfortunately, these 2D microarrays …

Cerebral small vessel disease (CSVD), which is a group of pathological processes affecting
cerebral microvessels, leads to functional loss in the elderly population and mostly presents …

Spinal cord injury (SCI) is a devastating condition with 250,000 to 500,000 new cases
globally each year. Respiratory infections, eg, pneumonia and influenza are the leading …

INTRODUCTION While elevated blood glial fibrillary acidic protein (GFAP) has been
associated with brain amyloid pathology, whether this association occurs in populations with …

Age-dependent cerebral small vessel disease (CSVD) is a common disease with a high
social burden characterized by heterogeneity of forms and frequent comorbidity with …

The prevalence of pain and dementia increases with age, affecting a significant percentage
of the population due to aging. Both pathologies are connected through the inflammatory …

Background and purpose The aim was to investigate the causal relationships of
inflammatory cytokines and serum metabolites in cerebral small vessel disease (CSVD) …

Spinal cord injury (SCI) is a devastating condition which negatively impacts an individual's
immune system. The spleen is a major immune organ, and its innervation is disrupted after …

Background Aging impacts both mental and physical health. The relationship between
cognitive decline and frailty in aged individuals remains unclear. This study aimed to …