Successful materials design for bone-tissue engineering requires an understanding of the
composition and structure of native bone tissue, as well as appropriate selection of …

Abstract β-tricalcium phosphate (β-TCP) is one the most used and potent synthetic bone
graft substitute. It is not only osteoconductive, but also osteoinductive. These properties …

Severe bone damage from diseases, including extensive trauma, fractures, and bone
tumors, cannot self-heal, while traditional surgical treatment may bring side effects such as …

The regulatory functions of the immune response in tissue healing, repair, and regeneration
have been evidenced in the last decade. Immune cells play central roles in immune …

In recent years, cellulose has attracted much attention because of its excellent properties,
such as its hydrophilicity, mechanical properties, biodegradability, biocompatibility, low cost …

Bone plates play a vital role in bone fracture healing by providing the necessary mechanical
fixation for fracture fragments through modulating biomechanical microenvironment adjacent …

One of the important challenges in bone tissue engineering is the development of
biodegradable bone substitutes with appropriate mechanical and biological properties for …

The regulatory role of the immune system in maintaining bone homeostasis and restoring its
functionality, when disturbed due to trauma or injury, has become evident in recent years …

So far, how to achieve the optimal regenerative repair of large load-bearing bone defects
using artificial bone grafts is a huge challenge in clinic. In this study, a strategy of combining …

Osteoinductivity of a biomaterial scaffold can notably enhance the bone healing
performance. In this study, we developed a biomimetic and hierarchically porous …