The diagnostics of inner ear diseases are primarily functional, but there is a growing interest
in inner ear biomarkers. The present scoping review aimed to elucidate gaps in the literature …

Recent findings of sequence convergence in the Prestin gene among some bats and
cetaceans suggest that parallel adaptations for high-frequency hearing have taken place …

超过50% 的耳聋由遗传基因缺陷所致, 伴随着基因组学技术的发展, 耳聋分子遗传学研究逐渐
成为耳科学研究的前沿领域. 新一代高通量测序技术的出现, 提供了以数据为导向的新的遗传性 …

A Comprehensive Network and Pathway Analysis of Human Deafne... : Otology & Neurotology
A Comprehensive Network and Pathway Analysis of Human Deafness Genes : Otology & …

Ménière's disease (MD) is a disorder of the inner ear characterized by an insidious onset
and aspecific symptoms, such as dizziness, vertigo, tinnitus, and hearing loss, that may …

Inherited myopathies are a heterogeneous group of disabling disorders with still barely
understood pathological mechanisms. Around 40% of afflicted patients remain without a …

Computational analyses of functions of gene sets obtained in microarray analyses or by
topical database searches are increasingly important in biology. To understand their …

Abstract Hereditary deafness affects 0.1% of individuals globally and is considered as one of
the most debilitating diseases of man. Despite recent advances, the molecular basis of …

Arachnomelia syndrome (AS), mainly found in Brown Swiss and Simmental cattle, is a
congenital lethal genetic malformation of the skeletal system. In this study, a network-based …

The gene Prestin encodes a motor protein that is thought to confer the high-frequency
sensitivity and selectivity that characterizes the mammalian auditory system. Recent …