Neural tube defects (NTDs) are common complex congenital malformations resulting from
failure of the neural tube closure during embryogenesis. It is established that folic acid …

Tetrahydrofolate (THF) polyglutamates are a family of cofactors that carry and chemically
activate one‐carbon units for biosynthesis. THF‐mediated one‐carbon metabolism is a …

Autism is a behaviorally defined neurodevelopmental disorder usually diagnosed in early
childhood that is characterized by impairment in reciprocal communication and speech …

Neural tube defects (NTDs) are common, severe congenital malformations whose causation
involves multiple genes and environmental factors. Although more than 200 genes are …

Context Prenatal folic acid supplements reduce the risk of neural tube defects and may have
beneficial effects on other aspects of neurodevelopment. Objective To examine associations …

Spina bifida, anencephaly, and encephalocele are commonly grouped together and termed
neural tube defects (NTD). Failure of closure of the neural tube during development results …

During the fifteen years since the bestselling first edition of Folate in Health and Disease
was published, there have been thousands of new research studies related to folate and its …

Inter-individual variation in patterns of DNA methylation at birth can be explained by the
influence of environmental, genetic and stochastic factors. This study investigates the …

Molecular biologists and geneticists alike now acknowledge that most common human
diseases with a genetic component are likely to have complex etiologies. Yet despite this …

Neural tube defects (NTDs), including anencephaly and spina bifida, arise from the failure of
neurulation during early embryonic development. Neural tube defects are common birth …