[HTML][HTML] Putative animal models of restless legs syndrome: A systematic review and evaluation of their face and construct validity

A Silvani, I Ghorayeb, M Manconi, Y Li, S Clemens - Neurotherapeutics, 2023 - Elsevier
Restless legs syndrome (RLS) is a sensorimotor disorder that severely affects sleep. It is
characterized by an urge to move the legs, which is often accompanied by periodic limb …

Manganese-enhanced magnetic resonance imaging: application in central nervous system diseases

J Yang, Q Li - Frontiers in Neurology, 2020 - frontiersin.org
Manganese-enhanced magnetic resonance imaging (MEMRI) relies on the strong
paramagnetism of Mn2+. Mn2+ is a calcium ion analog and can enter excitable cells through …

The role of BTBD9 in striatum and restless legs syndrome

S Lyu, H Xing, MP DeAndrade, Y Liu, PD Perez… - Eneuro, 2019 - eneuro.org
Restless legs syndrome (RLS) is a sensory-motor neurological disorder characterized by
uncomfortable sensations in the extremities, generally at night, which is often relieved by …

The role of BTBD9 in the cerebellum, sleep-like behaviors and the restless legs syndrome

S Lyu, H Xing, MP DeAndrade, PD Perez, F Yokoi… - Neuroscience, 2020 - Elsevier
Recent genome-wide association studies (GWAS) have found cerebellum as a top hit for
sleep regulation. Restless legs syndrome (RLS) is a sleep-related sensorimotor disorder …

MDMA-induced neurotoxicity of serotonin neurons involves autophagy and rilmenidine is protective against its pathobiology

LD Mercer, GC Higgins, CL Lau, AJ Lawrence… - Neurochemistry …, 2017 - Elsevier
Abstract Toxicity of 3, 4-methylenedioxymethamphetamine (MDMA) towards biogenic amine
neurons is well documented and in primate brain predominantly affects serotonin (5-HT) …

Cocaine differentially affects synaptic activity in memory and midbrain areas of female and male rats: an in vivo MEMRI study

PD Perez, G Hall, J Zubcevic, M Febo - Brain imaging and behavior, 2018 - Springer
Manganese enhanced magnetic resonance imaging (MEMRI) has been previously used to
determine the effect of acute cocaine on calcium-dependent synaptic activity in male rats …

In vivo long-lasting alterations of central serotonin transporter activity and associated dopamine synthesis after acute repeated administration of methamphetamine

WS Huang, GJ Chen, TH Tsai, CY Cheng, CY Shiue… - EJNMMI research, 2019 - Springer
Background Methamphetamine (METH)-associated alterations in the striatal dopamine (DA)
system or dopamine transport (DAT) have been identified in clinical and preclinical studies …

Amitriptyline Accelerates SERT Binding Recovery in a Rat 3,4-Methylenedioxymethamphetamine (MDMA) Model: In Vivo 4-[18F]-ADAM PET Imaging

CJ Tsai, CH Chiu, YY Kuo, WS Huang, TH Yu… - International journal of …, 2022 - mdpi.com
Numerous studies have confirmed that 3, 4-Methylenedioxymethamphetamine (MDMA)
produces long-lasting changes to the density of the serotonin reuptake transporter (SERT) …

Preliminary Results on the Long-Term Effects of Dextromethorphan on MDMA-Mediated Serotonergic Deficiency and Volumetric Changes in Primates Based on 4-[18 …

SHH Yeh, YY Kuo, WS Huang, CH Chiu… - Frontiers in …, 2022 - frontiersin.org
Alterations to the serotonergic system due to 3, 4-methylenedioxymethamphetamine
(MDMA)(ecstasy) consumption have been extensively documented. However, knowledge of …

Characterization of Mouse Models: Phenotypes with Implications on Restless Legs Syndrome

S Lyu - 2020 - search.proquest.com
Restless legs syndrome (RLS) is a sensory-motor sleep disorder characterized by an urge to
move and uncomfortable sensations in extremities, generally at night. Clinically, iron …