Magnetic resonance elastography in the study of neurodegenerative diseases

Y Feng, MC Murphy, E Hojo, F Li… - Journal of Magnetic …, 2024 - Wiley Online Library
Neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease
(PD) present a major health burden to society. Changes in brain structure and cognition are …

Magnetic Resonance Imaging and Nuclear Imaging of Parkinsonian Disorders: Where do we go from here?

FA Savoie, DJ Arpin… - Current …, 2024 - ingentaconnect.com
Parkinsonian disorders are a heterogeneous group of incurable neurodegenerative
diseases that significantly reduce quality of life and constitute a substantial economic …

Distinct cortical and subcortical predictors of Purdue Pegboard decline in Parkinson's disease and atypical parkinsonism

BJ Wilkes, ER Tobin, DJ Arpin, W Wang… - npj Parkinson's …, 2023 - nature.com
Objective measures of disease progression are critically needed in research on Parkinson's
disease (PD) and atypical Parkinsonism but may be hindered by both practicality and cost …

Fiber-specific micro-and macroscopic white matter alterations in progressive supranuclear palsy and corticobasal syndrome

W Uchida, K Kamagata, C Andica… - npj Parkinson's …, 2023 - nature.com
Progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS) are characterized
by progressive white matter (WM) alterations associated with the prion-like spreading of four …

Non-motor symptoms in multiple system atrophy: A comparative study with Parkinson's disease and progressive supranuclear palsy

WZ Hu, LX Cao, JH Yin, XS Zhao, YS Piao… - Frontiers in …, 2023 - frontiersin.org
Background Non-motor symptoms (NMS) are compulsory clinical features for the clinical
diagnosis of multiple system atrophy (MSA), some of which precede motor symptoms onset …

Cortico-basal ganglia white matter microstructure is linked to restricted repetitive behavior in autism spectrum disorder

BJ Wilkes, DB Archer, AL Farmer, C Bass, H Korah… - Molecular Autism, 2024 - Springer
Background Restricted repetitive behavior (RRB) is one of two behavioral domains required
for the diagnosis of autism spectrum disorder (ASD). Neuroimaging is widely used to study …

Diffusion MRI relates to plasma Aβ42/40 in PET negative participants without dementia

JC DeSimone, W Wang, DA Loewenstein… - Alzheimer's & …, 2024 - Wiley Online Library
INTRODUCTION Magnetic resonance imaging (MRI) biomarkers are needed for indexing
early biological stages of Alzheimer's disease (AD), such as plasma amyloid‐β (Aβ42/40) …

Longitudinal Free‐Water Changes in Dementia with Lewy Bodies

SY Chiu, R Chen, W Wang, MJ Armstrong… - Movement …, 2024 - Wiley Online Library
Background Diffusion‐weighted magnetic resonance imaging (dMRI) examines tissue
microstructure integrity in vivo. Prior dementia with Lewy bodies (DLB) diffusion tensor …

Increased free water in the putamen in idiopathic REM sleep behavior disorder

D Zhang, L Zhou, J Yao, Y Shi, H He, H Wei… - Movement …, 2023 - Wiley Online Library
Background It has been suggested that the loss of nigrostriatal dopaminergic axon terminals
occurs before the loss of dopaminergic neurons in the substantia nigra (SN) in Parkinson's …

Functional and free-water imaging in rapid eye movement behaviour disorder and Parkinson's disease

ER Tobin, DJ Arpin, MB Schauder… - Brain …, 2024 - academic.oup.com
It is established that one of the best predictors of a future diagnosis of Parkinson's disease is
a current diagnosis of rapid eye movement behaviour disorder (RBD). In such patients, this …