Tracing the footsteps of autophagy in computational biology
Autophagy plays a crucial role in maintaining cellular homeostasis through the degradation
of unwanted materials like damaged mitochondria and misfolded proteins. However, the …
of unwanted materials like damaged mitochondria and misfolded proteins. However, the …
Latent tuberculosis and computational biology: A less-talked affair
Tuberculosis (TB) is a pervasive and devastating air-borne disease caused by the
organisms belonging to the Mycobacterium tuberculosis (Mtb) complex. Currently, it is the …
organisms belonging to the Mycobacterium tuberculosis (Mtb) complex. Currently, it is the …
[图书][B] Big Data Analytics in Chemoinformatics and Bioinformatics: With Applications to Computer-Aided Drug Design, Cancer Biology, Emerging Pathogens and …
SC Basak, M Vračko - 2022 - books.google.com
Big Data Analytics in Chemoinformatics and Bioinformatics: With Applications to Computer-
Aided Drug Design, Cancer Biology, Emerging Pathogens and Computational Toxicology …
Aided Drug Design, Cancer Biology, Emerging Pathogens and Computational Toxicology …
konnect2prot: a web application to explore the protein properties in a functional protein–protein interaction network
Motivation The regulation of proteins governs the biological processes and functions and,
therefore, the organisms' phenotype. So there is an unmet need for a systematic tool for …
therefore, the organisms' phenotype. So there is an unmet need for a systematic tool for …
A data-driven multilayer approach for the identification of potential therapeutic targets in non-alcoholic steatohepatitis
The traditional computational methods of investigating a disease system are limited by the
inability to look at the in-depth association between different molecular layers. For instance …
inability to look at the in-depth association between different molecular layers. For instance …
Bidirectional regulation between AP-1 and SUMOylation pathway genes modulates inflammatory signaling during Salmonella infection
ABSTRACT Post-translational modifications (PTMs), such as SUMOylation, are known to
modulate fundamental processes of a cell. Infectious agents such as Salmonella …
modulate fundamental processes of a cell. Infectious agents such as Salmonella …
BAG6 is a novel player in controlling nonalcoholic steatohepatitis: result from a comprehensive in-silico study
Nonalcoholic steatohepatitis, or NASH, is a multifactorial disease characterized by hepatic
lipid accumulation, inflammation, cell death, and fibrosis, and an efficacious pharmaceutical …
lipid accumulation, inflammation, cell death, and fibrosis, and an efficacious pharmaceutical …
Extracting predictors for lung adenocarcinoma based on Granger causality test and stepwise character selection
X Fan, Y Wang, XQ Tang - BMC bioinformatics, 2019 - Springer
Background Lung adenocarcinoma is the most common type of lung cancer, with high
mortality worldwide. Its occurrence and development were thoroughly studied by high …
mortality worldwide. Its occurrence and development were thoroughly studied by high …
Recent advances in drug development targeting cancer metabolism
Cancer cell proliferation and their adaptation to tough environments depend critically on
metabolic pathways. The pathological, phenotypic, and structural level understanding of …
metabolic pathways. The pathological, phenotypic, and structural level understanding of …
Bidirectional regulation between AP-1 and SUMO genes modulates inflammatory signalling during Salmonella Typhimurium infection
Abstract Gram-negative bacterium Salmonella Typhimurium (STm) is the causative agent of
gastroenteritis. Among the various gut pathogens, STm is still one of the most frequent …
gastroenteritis. Among the various gut pathogens, STm is still one of the most frequent …