Osteoarthritis (OA) is a degenerative joint disease characterized by low-grade inflammation
and high levels of clinical heterogeneity. Aberrant chondrocyte metabolism is a response to …

Understanding of the basis of osteoarthritis (OA) has seen some interesting advancements
in recent years. It has been observed that cartilage degeneration is preceded by …

Objective Obesity was once considered a risk factor for knee osteoarthritis (OA) primarily for
biomechanical reasons. Here we provide an additional perspective by discussing how …

Extracellular vesicles (EVs) are highly diverse nanoscale membrane-bound structures
released from different cell types into the extracellular environment. They play essential …

Background The successful use of rose hip for the treatment of osteoarthritis is well
documented. Several randomized placebo controlled double-blind studies, as mono or …

Osteoarthritis (OA) is increasing in prevalence and has a severe impact on patients' lives.
However, our understanding of biomarkers driving OA risk remains limited. We developed a …

Exosomes and other classes of extracellular vesicles (EVs) have gained interest due to their
role in cell-to-cell communication. Knowledge of the molecular content of EVs may provide …

Osteoarthritis (OA) is the most common form of arthritis resulting in joint discomfort and
disability, culminating in decline in life quality. Attention has been drawn in recent years to …

Objective Osteoarthritis (OA), the most encountered arthritis form, result from degeneration of
articular cartilage. Obesity is accepted as a significant risk factor for knee OA (KOA). In this …

Objective Osteoarthritis is a heterogeneous disease. The objective was to compare
differences in underlying cellular mechanisms and endogenous repair pathways between …