[HTML][HTML] Imaging perivascular space structure and function using brain MRI

G Barisano, KM Lynch, F Sibilia, H Lan, NC Shih… - Neuroimage, 2022 - Elsevier
In this article, we provide an overview of current neuroimaging methods for studying
perivascular spaces (PVS) in humans using brain MRI. In recent years, an increasing …

Characterization of the hemodynamic response function in white matter tracts for event-related fMRI

M Li, AT Newton, AW Anderson, Z Ding… - Nature …, 2019 - nature.com
Accurate estimates of the BOLD hemodynamic response function (HRF) are crucial for the
interpretation and analysis of event-related functional MRI data. To date, however, there …

Image processing approaches to enhance perivascular space visibility and quantification using MRI

F Sepehrband, G Barisano, N Sheikh-Bahaei… - Scientific reports, 2019 - nature.com
Imaging the perivascular spaces (PVS), also known as Virchow-Robin space, has significant
clinical value, but there remains a need for neuroimaging techniques to improve mapping …

The influence of brain iron on myelin water imaging

C Birkl, AM Birkl-Toeglhofer, V Endmayr, R Höftberger… - Neuroimage, 2019 - Elsevier
With myelin playing a vital role in normal brain integrity and function and thus in various
neurological disorders, myelin sensitive magnetic resonance imaging (MRI) techniques are …

Perivascular space fluid contributes to diffusion tensor imaging changes in white matter

F Sepehrband, RP Cabeen, J Choupan, G Barisano… - Neuroimage, 2019 - Elsevier
Diffusion tensor imaging (DTI) has been extensively used to map changes in brain tissue
related to neurological disorders. Among the most widespread DTI findings are increased …

Myelin water imaging depends on white matter fiber orientation in the human brain

C Birkl, J Doucette, M Fan… - Magnetic resonance …, 2021 - Wiley Online Library
Purpose The multi‐exponential T2 decay of the MRI signal from cerebral white matter can be
separated into short T2 components related to myelin water and long T2 components related …

[HTML][HTML] Orientation dependence of R2 relaxation in the newborn brain

LM Bartels, J Doucette, C Birkl, Y Zhang, AM Weber… - NeuroImage, 2022 - Elsevier
In MRI the transverse relaxation rate, R 2= 1/T 2, shows dependence on the orientation of
ordered tissue relative to the main magnetic field. In previous studies, orientation effects of R …

White matter neuroplasticity: Motor learning activates the internal capsule and reduces hemodynamic response variability

TO Frizzell, LA Grajauskas, CC Liu… - Frontiers in Human …, 2020 - frontiersin.org
Numerous studies have noted the importance of white matter changes in motor learning, but
existing literature only focuses on structural and microstructural MRI changes, as there are …

Dependence of resting-state fMRI fluctuation amplitudes on cerebral cortical orientation relative to the direction of B0 and anatomical axes

O Viessmann, K Scheffler, M Bianciardi, LL Wald… - Neuroimage, 2019 - Elsevier
Functional magnetic resonance imaging (fMRI) is now capable of sub-millimetre scale
measurements over the entire human brain, however with such high resolutions each voxel …

The role of iron and myelin in orientation dependent R2* of white matter

D Kor, C Birkl, S Ropele, J Doucette, T Xu… - NMR in …, 2019 - Wiley Online Library
Brain myelin and iron content are important parameters in neurodegenerative diseases such
as multiple sclerosis (MS). Both myelin and iron content influence the brain's R2* relaxation …