Brain-expressed exons under purifying selection are enriched for de novo mutations in autism spectrum disorder

M Uddin, K Tammimies, G Pellecchia, B Alipanahi… - Nature …, 2014 - nature.com
A universal challenge in genetic studies of autism spectrum disorders (ASDs) is determining
whether a given DNA sequence alteration will manifest as disease. Among different …
被引用次数：176 相关文章

Brain-expressed exons under purifying selection are enriched for de novo mutations in autism spectrum disorder.

M Uddin, K Tammimies, G Pellecchia… - Nature …, 2014 - search.ebscohost.com
A universal challenge in genetic studies of autism spectrum disorders (ASDs) is determining
whether a given DNA sequence alteration will manifest as disease. Among different …
[PDF] researchgate.net

[PDF][PDF] Brain-expressed exons under purifying selection are enriched for de novomutations in autism spectrum disorder

M Uddin, K Tammimies, G Pellecchia, B Alipanahi… - researchgate.net
We classified exons in two ways to construct an exon transcriptomemutation contingency
index (Supplementary Note):(i) exon expression levels were discretized into classes with …

Brain-expressed exons under purifying selection are enriched for de novo mutations in autism spectrum disorder.

M Uddin, K Tammimies, G Pellecchia, B Alipanahi… - Nature …, 2014 - europepmc.org
Brain-expressed exons under purifying selection are enriched for de novo mutations in autism
spectrum disorder. - Abstract - Europe PMC Sign in | Create an account https://orcid.org …

Brain-expressed exons under purifying selection are enriched for de novo mutations in autism spectrum disorder.

M Uddin, K Tammimies, G Pellecchia, B Alipanahi… - Nature …, 2014 - go.gale.com
Stephen Scherer and colleagues report an inverse relationship between exon transcription
levels in the developing brain and the burden of rare missense mutations. Using these data …

Brain-expressed exons under purifying selection are enriched for de novo mutations in autism spectrum disorder

M Uddin, K Tammimies, G Pellecchia… - Nature …, 2014 - pubmed.ncbi.nlm.nih.gov
A universal challenge in genetic studies of autism spectrum disorders (ASDs) is determining
whether a given DNA sequence alteration will manifest as disease. Among different …
[PDF] kidsbrainhealth.ca

[PDF][PDF] Brain-expressed exons under purifying selection are enriched for de novomutations in autism spectrum disorder

M Uddin, K Tammimies, G Pellecchia, B Alipanahi… - Nature - kidsbrainhealth.ca
We classified exons in two ways to construct an exon transcriptomemutation contingency
index (Supplementary Note):(i) exon expression levels were discretized into classes with …
[PDF] academia.edu

[PDF][PDF] Brain-expressed exons under purifying selection are enriched for de novomutations in autism spectrum disorder

M Uddin, K Tammimies, G Pellecchia… - NATURE …, 2014 - academia.edu
We classified exons in two ways to construct an exon transcriptomemutation contingency
index (Supplementary Note):(i) exon expression levels were discretized into classes with …
[PDF] academia.edu

[PDF][PDF] Brain-expressed exons under purifying selection are enriched for de novomutations in autism spectrum disorder

M Uddin, K Tammimies, G Pellecchia, B Alipanahi… - academia.edu
We classified exons in two ways to construct an exon transcriptomemutation contingency
index (Supplementary Note):(i) exon expression levels were discretized into classes with …

Brain-expressed exons under purifying selection are enriched for de novo mutations in autism spectrum disorder

M Uddin, K Tammimies, G Pellecchia, B Alipanahi… - Nature …, 2014 - go.gale.com
A universal challenge in genetic studies of autism spectrum disorders (ASDs) is determining
whether a given DNA sequence alteration will manifest as disease. Among different …