Case study: the role of mechanistic network models in systems toxicology

J Hoeng, M Talikka, F Martin, A Sewer, X Yang… - Drug Discovery …, 2014 - Elsevier
Highlights•Biological network models enable a mechanistic understanding of high-
throughput data.•Network response can be quantified for the impact of a given stimulus.•The …

Case study: the role of mechanistic network models in systems toxicology

J Hoeng, M Talikka, F Martin, A Sewer, X Yang… - Drug Discovery …, 2014 - infona.pl
Twenty first century systems toxicology approaches enable the discovery of biological
pathways affected in response to active substances. Here, we briefly summarize current …

Case study: the role of mechanistic network models in systems toxicology.

J Hoeng, M Talikka, F Martin, A Sewer, X Yang… - Drug Discovery …, 2013 - europepmc.org
Twenty first century systems toxicology approaches enable the discovery of biological
pathways affected in response to active substances. Here, we briefly summarize current …

Case study: the role of mechanistic network models in systems toxicology

J Hoeng, M Talikka, F Martin, A Sewer… - Drug discovery …, 2014 - pubmed.ncbi.nlm.nih.gov
Twenty first century systems toxicology approaches enable the discovery of biological
pathways affected in response to active substances. Here, we briefly summarize current …