… and 5-amino salicylic acid, was first introduced to treat rheumatoid arthritis in 1930 (for review
see … Since the recognition of the side effects of sulphasalazine on male fertility, it has been …

… It consists of sulphapyridine (SP) linked to 5 amino salicylic acid (5-ASA) by an azo bond. 5-
… sulfasalazine is capable of causing deleterious effect on reproductive parameters in male …

… review of the pharmacology, modes of action, side effects, … Both SSZ and sulfapyridine
cross the placenta and are found … properties, whereas the salicylate component acts as an anti-…

The sulfonamide (sulphonamide) antibacterial drugs, sulfapyridine (SP) and sulfamethoxypyridazine
(SMP) are structurally related to para-aminobenzoic acid (PABA). Sulfonamides do …

… reviews the indications, contraindications, mode of action, … have not responded adequately
with salicylates or other non-… whether sulfasalazine or its metabolites such as sulfapyridine …

… 5-ASA bonded to sulfapyridine. Sulfasalazine is converted to the sulfapyridine and 5-ASA
moieties … portions of the technical review. The guideline panel and the authors of the technical …

… This review will summarize the literature on the use of IBD … In males, the sulfapyridine moiety
of sulfasalazine has been implicated in impairing sperm maturation, causing reduced sperm …

… It is formed by combining sulfapyridine and salicylate with an azo bond [10]. Sulfasalazine is
used … A copy of the written consent is available for review by the Editorial office/Chief Editor/…

… With this study we aimed to review the literature relating to microbial drug … [salicylic acid]
linked to the antimicrobial drug [sulfanomide]. Sulfasalazine was made by linking sulfapyridine […

… of sulfapyridine moiety in the newer 5-ASAs possibly mitigates the adverse effect of sulfasalazine
on male fertility [… Population-based studies in this systematic review and meta-analysis …