Viral dependence on cellular ion channels–an emerging anti-viral target?
… targeting ion channels pharmacologically can impede virus life cycles. Here, we discuss
current examples of virus–ion channel interactions and the potential of targeting ion channel …
current examples of virus–ion channel interactions and the potential of targeting ion channel …
[PDF][PDF] Viral ion channels as models for ion transport and targets for antiviral drug action
DLH Pinto - FEBS letters, 2004 - core.ac.uk
… M2 proteins in order to realize their potential as antiviral targets. In£uenza A and in£uenza …
that encode the small M2 ion channel proteins [2]. These proton channels are found in the …
that encode the small M2 ion channel proteins [2]. These proton channels are found in the …
Validation of coronavirus E proteins ion channels as targets for antiviral drugs
L Wilson, P Gage, G Ewart - The Nidoviruses: Toward Control of SARS …, 2006 - Springer
… with viral ion channels and their important role in viral replication, we hypothesized that
coronavirus E proteins have ion channel activity, and compounds that block these channels may …
coronavirus E proteins have ion channel activity, and compounds that block these channels may …
Viroporins: structure, function and potential as antiviral targets
C Scott, S Griffin - Journal of General Virology, 2015 - microbiologyresearch.org
… Ultimately, given the successes of drugs targeting ion channels in other areas of medicine,
unlocking the therapeutic potential of viroporins represents a valuable goal for many of the …
unlocking the therapeutic potential of viroporins represents a valuable goal for many of the …
[HTML][HTML] Ion channels as therapeutic targets for viral infections: further discoveries and future perspectives
FW Charlton, HM Pearson, S Hover, JD Lippiat… - Viruses, 2020 - mdpi.com
… role of ion channels during viral lifecycles, describe the recently identified ion channel drugs
that … that ion channel inhibitors represent a new antiviral strategy. Whilst toxicity profiles for …
that … that ion channel inhibitors represent a new antiviral strategy. Whilst toxicity profiles for …
[HTML][HTML] Viral proteins function as ion channels
… mechanisms, and also discuss viral ion channel protein serving as a potential drug target. …
on virus ion channels was that they may serve as ideal anti-viral drug targets. Amantadine was …
on virus ion channels was that they may serve as ideal anti-viral drug targets. Amantadine was …
[HTML][HTML] Unravelling the immunomodulatory effects of viral ion channels, towards the treatment of disease
S Gargan, NJ Stevenson - Viruses, 2021 - mdpi.com
… discuss the current antiviral therapies that target them; continually … ) amiloride (HMA) targets
the ion channel activity of Vpu and … Interestingly, while this inhibitor targets the ion channel …
the ion channel activity of Vpu and … Interestingly, while this inhibitor targets the ion channel …
Coronaviral ion channels as target for Chinese herbal medicine
… that viral ion channels, in general, may be good targets for the development of antiviral agents,
… of known antiviral phytochemicals on the ionchannel-forming 3a protein of coronavirus. …
… of known antiviral phytochemicals on the ionchannel-forming 3a protein of coronavirus. …
Genistein as antiviral drug against HIV ion channel
… tool to screen drugs for their potency in inhibition of ion channel activity. The viral protein U-…
that viral ion channels, in general, may be a good target for development of antiviral agents, …
that viral ion channels, in general, may be a good target for development of antiviral agents, …
Viral targets of acylguanidines
EV Gazina, S Petrou - Drug discovery today, 2012 - Elsevier
… antiviral actions of acylguanidines, a class of compounds with a remarkable range of inhibitory
targets, … Thus it is not clear whether prM or M form ion channels, and an antiviral activity of …
targets, … Thus it is not clear whether prM or M form ion channels, and an antiviral activity of …
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